The Efficacy and Safety of the Fractional Radiofrequency Technique for the Treatment of Atrophic Acne Scar in Asians: a Meta-Analysis.

The Efficacy and Safety of the Fractional Radiofrequency Technique for the Treatment of Atrophic Acne Scar in Asians: a Meta-Analysis.

J Cosmet Laser Ther. 2017 Apr 07;:

Authors: Dai R, Xie H, Hua W, Li XH, Li BD

Abstract
BACKGROUND: The fractional radiofrequency technique (fRF) is a recently emerged technique. However, the exact outcomes of fRF for treating atrophic acne scar in Asians are still unclear now.
OBJECTIVE: To compare the clinical outcomes of fRF with the fractional laser technique in Asians with atrophic acne scar.
MATERIALS AND METHODS: The databases MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and Chinese National Knowledge Infrastructure (CNKI) were searched. Main clinical outcomes were participant-reported scar improvement, investigator-reported scar improvement, post-inflammatory hyperpigmentation (PIH), erythema duration, scab duration and the pain level.
RESULT: Six randomized controlled trials were included in this meta-analysis. The scar improvement was similar in both groups regarding participant-reported scar improvement (p=0.48) and investigator-reported scar improvement (p=0.89). However, fRF led less occurrence of PIH in comparison with the laser group (p<0.001). The average duration of erythema was shorter in fRF group than the laser group (p<0.001). The mean time for debridement was shorter in fRF group than the carbon dioxide fractional laser system (p=0.02). The pain level did not differ significantly in two groups (p=0.53).
CONCLUSION: Although some bias exists in our study, fRF appears to be a superior alternative for the treatment of atrophic acne scar in Asians.

PMID: 28388236 [PubMed - as supplied by publisher]

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