The length and complexity of mesentery are related to the locoregional recurrence of the gastrointestinal tumor

Publication date: Available online 22 April 2017
Source:Medical Hypotheses
Author(s): Jie Shen, Daxing Xie, Jianping Gong
Local-regional relapse is the main recurrence pattern of gastrointestinal tumor, and leads to poor prognosis. It is well established that, the major risk factor of locoregional recurrence is the minimal tumor residual, which cannot be completely removed via operation procedure. Since 1982, Heald et al. put forward total mesorectal excision (TME), the relapse rate of rectal cancer have significantly decreased. This indicates that, complete mesentery excision is an effective method to reduce tumor residual and improve patients' prognosis. However, the length and complexity of mesentery in different segments of GI tract are not the same, this leads to the different difficulty of mesentery dissection in individual digestive tract. Meanwhile, there is an obvious distinction of local relapse rate in different gastrointestinal organ. Therefore, we assume that the length and complexity of mesentery may be the risk factor of the locoregional recurrence rate of the gastrointestinal tumor.



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