Undifferentiated pleomorphic sarcoma of the vocal fold.

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Undifferentiated pleomorphic sarcoma of the vocal fold.

Ear Nose Throat J. 2016 Dec;95(12):E12-E14

Authors: Jeong CY, Kim CS

Abstract
Undifferentiated pleomorphic sarcoma, previously called malignant fibrous histiocytoma, usually arises in the extremities and retroperitoneum. Primary laryngeal undifferentiated pleomorphic sarcoma is very rare, with only 63 cases having been reported in the literature as of 2015. The disease has a poor prognosis because of problems with local recurrence and metastasis. Wide resection has been recommended as a treatment modality in previous reports. We report a case of undifferentiated pleomorphic sarcoma of the vocal fold in a 64-year-old man presenting with rapid growth. The lesion was treated with type III microlaryngeal surgery followed by radiation therapy. The patient's voice was good enough for social communication, and there was no evidence of recurrence on regular examination.

PMID: 27929601 [PubMed - indexed for MEDLINE]

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