Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6

Publication date: Available online 4 May 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Xia Hua, Xiaoyong Yuan, Yonghao Li, Hui Chen, Jin Yuan, Silvia Tanumiharjo, Fang Bian, Lishi Su, Yanhua Hong, Yizhi Liu, Wei Chi

Teaser

We reveal novel discoveries of an innate immune pathway mediated by the imbalanced activation of NLRP3 and NLRP6 promoted by caspase-8 activation in AB and secondary dry eye and create new intervention strategies to treat inflammatory diseases.


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