Extraneural Metastases From Desmoplastic Medulloblastoma Masquerading as Lymphoma.

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Extraneural Metastases From Desmoplastic Medulloblastoma Masquerading as Lymphoma.

Clin Nucl Med. 2017 May;42(5):354-357

Authors: Mahajan A, Paul P, Sridhar E, Rangarajan V, Gupta T, Chinnaswamy G, Moiyadi A, Jalali R

Abstract
Medulloblastoma is a WHO grade IV neoplasm that is usually restricted to the central nervous system, with metastasis occurring along the neuraxis through the ventricular system and cerebrospinal fluid. Extraneural metastasis is rare, usually occurs in bones/lymph nodes, and carries poor prognosis. We report multimodal imaging in a 14-year-old boy with desmoplastic medulloblastoma having multiple extraneural nodal and skeletal metastases, which was misdiagnosed as lymphoma. This case highlights the importance of understanding tumor biology with active clinical and radiological surveillance that is useful in early detection of extraneural metastasis of this aggressive tumor that helps in advocating appropriate and timely treatment.

PMID: 28263211 [PubMed - indexed for MEDLINE]

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