Treatment of Neurogenic Cough with Tramadol: A Pilot Study.

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Treatment of Neurogenic Cough with Tramadol: A Pilot Study.

Otolaryngol Head Neck Surg. 2017 Apr 01;:194599817703949

Authors: Dion GR, Teng SE, Achlatis E, Fang Y, Amin MR

Abstract
This study employs validated cough assessment tools to prospectively determine the impact of tramadol on cough severity and quality of life in subjects with neurogenic cough. The study was a prospective case series with planned data collection at a tertiary care academic medical center laryngology practice. Sixteen consecutive collected subjects with neurogenic cough prospectively completed pre- and posttreatment validated cough assessment tools, the cough severity index (CSI) and Leicester Cough Questionnaire (LCQ). All subjects in the study reported at least some improvement in their cough symptoms. In a Wilcoxon signed rank test that compared paired results, CSI scores improved from 23 to 14 and LCQ scores improved from 74 to 103 ( P = .003 and P = .005, respectively). This small preliminary assessment suggests that tramadol warrants additional evaluation as a treatment for neurogenic cough.

PMID: 28463539 [PubMed - as supplied by publisher]

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