Unusual Presentation of Relapse in Neuroblastoma: Pancreatic Metastases Detected by 123I-MIBG Scintigraphy.

Unusual Presentation of Relapse in Neuroblastoma: Pancreatic Metastases Detected by 123I-MIBG Scintigraphy.

Clin Nucl Med. 2017 May 19;:

Authors: Villani MF, D'Andrea ML, Castellano A, Pizzoferro M, Garganese MC

Abstract
Neuroblastoma is the most common extracranial solid tumor in children and accounts for 8% to 10% of all childhood cancers. The spread of metastases is both lymphatic and hematogenous. Hematogenous route occurs most commonly in bone marrow and cortical bone; pancreatic metastases are very rare, and there are few reports about this topic in medical literature. We report the case of a 14-year-old boy who suffers a third relapse of neuroblastoma: in this patient I-MIBG confirms that lesions detected by CT were due to a relapse in pancreatic tissue and influenced subsequent therapeutic management.

PMID: 28525458 [PubMed - as supplied by publisher]

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