Rakesh Bhadade, Minal Harde, Rosemarie deSouza, Ashwini More, Ramesh Bharmal
Annals of African Medicine 2017 16(3):107-113
Background: Nosocomial pneumonia poses great challenge to an intensivist. Detailed information about hospital-acquired pneumonia (HAP) and ventilator-acquired pneumonia (VAP) is crucial for prevention and optimal management, thus improving quality Intensive Care Unit (ICU) care. Hence, we aimed to study the current trend of nosocomial pneumonia in ICU. Materials and Methods: It was a prospective observational cohort study, conducted in the ICU of a tertiary care teaching public hospital over a period of 18 months. We studied clinical profile and outcome of 120 adult patients who developed VAP/HAP during the study period. We also analyzed the causative organisms, antibiotic sensitivity, and resistance pattern in these patients. Results: Out of 120 patients, 29 patients were HAP and 91 patients were VAP. Mortality was 60% (72), and development of VAP and requirement of mechanical ventilation showed significant association with mortality (P < 0.00001). Most common organism causing HAP was Staphylococcus aureus (43.4%) and VAP was Klebsiella pneumoniae (49%). Maximum antibiotic sensitivity was found to piperacillin + tazobactam (58.8%), followed by imipenem (49.5%) and meropenem (41.8%), whereas maximum antibiotic resistance was found to cefepime (95.1%), followed by ceftazidime and amoxicillin (91.2%). Conclusion: Nosocomial pneumonia showed high incidence (17.44%) and mortality (60%). Common organisms identified were S. aureus and K. pneumoniae. Resistance was high for commonly used antibiotics and high antibiotic sensitivity for piperacillin + tazobactam and carbapenem. Contexte: La pneumonie nosocomiale pose un grand défi à un intensiviste. Des informations détaillées sur la pneumonie acquise dans les hôpitaux (HAP) et la pneumonie acquise par le ventilateur (VAP) sont essentielles pour la prévention et la gestion optimale, améliorant ainsi les soins de soins intensifs de qualité (UTI). Par conséquent, nous avons cherché à étudier la tendance actuelle de la pneumonie nosocomiale en UTI. Matériaux et méthodes: il s'agissait d'une étude de cohorte observationnelle prospective menée dans l'UCI d'un hôpital public d'enseignement tertiaire sur une période de 18 mois. Nous avons étudié le profil clinique et le résultat de 120 patients adultes qui ont développé le VAP / HAP pendant la période d'étude. Nous avons également analysé les organismes responsables, la sensibilité aux antibiotiques et le modèle de résistance chez ces patients. Résultats: Sur 120 patients, 29 patients étaient HAP et 91 patients étaient VAP. La mortalité était de 60% (72), et le développement du VAP et l'exigence de ventilation mécanique ont montré une association significative avec la mortalité (P < 0,00001). L'organisme le plus fréquent causant HAP était Staphylococcus aureus (43,4%) et VAP était Klebsiella pneumoniae (49%). Une sensibilité antibiotique maximale a été observée chez la pipéracilline + tazobactam (58,8%), suivie de l'imipénème (49,5%) et du méropénem (41,8%), alors que la résistance antibiotique maximale a été observée à cefépime (95,1%), suivie de ceftazidime et de l'amoxicilline (91,2%) . Conclusion: la pneumonie nosocomiale a montré une incidence élevée (17,44%) et la mortalité (60%). Les organismes communs identifiés étaient S. aureus et K. pneumoniae. La résistance était élevée pour les antibiotiques couramment utilisés et une forte sensibilité aux antibiotiques pour la pipéracilline + le tazobactam et le carbapénème.
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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- Tuberculous meningoencephalitis associated with br...
- Response to Comment on Ohlenforst et al.
- Comment on Ohlenforst et al. (2016) Exploring the ...
- Associative Learning Should Go Deep
- Fluorescein sodium-guided surgery of parotid gland...
- Fluorescein sodium-guided surgery of parotid gland...
- Tuberculous meningoencephalitis associated with br...
- Dermatological learning needs among aboriginal hea...
- Maculopapular type drug eruption caused by garenox...
- Rapid response to clinical symptoms in early psori...
- Lepromatous leprosy with Lucio's phenomenon
- Necrobiosis lipoidica following Q-switched laser t...
- Pyoderma gangrenosum arising during treatment of p...
- Rapid response to clinical symptoms in early psori...
- Dermatological learning needs among aboriginal hea...
- Lepromatous leprosy with Lucio's phenomenon
- Maculopapular type drug eruption caused by garenox...
- Necrobiosis lipoidica following Q-switched laser t...
- Pyoderma gangrenosum arising during treatment of p...
- Febrile headache and leg weakness as the initial s...
- Letter to the editor regarding “Blood count values...
- From Japan to Europe: the importance to assess exc...
- The Influence of Intraoperative Testing on Surgica...
- Outcomes and Time to Emergence of Auditory Skills ...
- The Hannover Coupler: Controlled Static Prestress ...
- Critical Ischemia Times and The Effect of Novel Pr...
- Targeted Next-generation Sequencing in Brazilian C...
- Pharmacokinetics and Clinical Outcomes of Generic ...
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- Cost analysis of microtia treatment in the Netherl...
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- The long-term impact of oncoplastic breast conserv...
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- A novel chalcone derivative, LQFM064, induces brea...
- Clinical and dermoscopic features of targetoid hae...
- Pattern of skin diseases among patients attending ...
- Infundibulocystic basal cell carcinoma of the eyelid
- Pattern of skin diseases among patients attending ...
- Infundibulocystic basal cell carcinoma of the eyelid
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- A high sensitive visible light-driven photoelectro...
- Quantitative ratiometric phosphorescence hypoxia–s...
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- Editorial Board
- Carbon nanostructures as immobilization platform f...
- Recent advances in transition-metal dichalcogenide...
- Dual signal amplification strategy of Au nanopatic...
- Enzyme-less electrochemical displacement heterogen...
- A real-time-range potentiostat coupled to nano-Au-...
- Aging and Confidence Judgments in Item Recognition.
- Working Memory Capacity and the Antisaccade Task: ...
- Effect of orthognathic surgery on profile esthetic...
- Incidence and severity of gingival invaginations a...
- Effects of combined orthodontic-orthognathic treat...
- Electrochemical Carbon Based Nanosensors: A Promis...
- Bilateral inner ear damage after electrical injury...
- Effect of orthognathic surgery on profile esthetic...
- Incidence and severity of gingival invaginations a...
- Effects of combined orthodontic-orthognathic treat...
- Ultrasound Risk Categories for Thyroid Nodules and...
- Ultrasound Risk Categories for Thyroid Nodules and...
- Retrospective study of intranasal dexmedetomidine ...
- Comparison of home sleep apnea testing versus labo...
- Evaluation of locked plate in the osteosynthesis o...
- Primary hyperparathyroidism in pregnancy
- Randomized controlled trials: Ethical and scientif...
- Low back pain in pregnant women attending antenata...
- Evaluation of neutrophil gelatinase-associated lip...
- Sonographic assessment of urolithiasis in universi...
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- Cross-sectional, observational study of anterior s...
- A profile of adverse effects of antihypertensive m...
- Overview of extremity musculoskeletal neoplasms at...
- Effect of analgesia on the changes in respiratory ...
- Atherogenic index of plasma for the assessment of ...
- Animal-derived natural products of Sowa Rigpa medi...
- Alterations in liver marker enzymes and recovery a...
- Parasites and pollution: the effectiveness of tiny...
- Imaging Profile of the Ear in Hearing Loss Patient...
- Morphometric Analysis of the Orbital Process of th...
- A Prospective, Randomized Comparison of Lower Eyel...
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