Healing lotion formula with proven superiority to Rx and therapeutic moisturizing lotions translates into improvements in stratum corneum biology and barrier resilience

Barrier integrity and therefore skin dryness falls along a spectrum—from normal to atopic—based on a number of genetic and environmental factors. The outermost layers of the epidermis (stratum corneum, SC) are key for maintaining skin health and barrier quality. For moderate to severe dry skin, the ideal moisturizer should provide initial and sustained hydration as well as repairing the barrier from within. Barrier resilience is indicated by improved SC parameters on regression. The goals of this research were to compare improvement in hydration from a healing test lotion with a combination of high glycerin, petrolatum, and fatty acid versus Rx and marketed therapeutic lotions and to demonstrate improvement in barrier resilience.

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