Synchrotron radiation μCT and histology evaluation of bone-to-implant contact

Bone-to-implant contact (BIC) in loaded implants is proved to be 60–70% when using light microscopy, and 10% less in unloaded implants (Albrektsson 2008). However, histology studies in mini-pigs, pigs, and dogs show comparable BIC in unloaded implants ranging between 49% and 77.2% after healing periods of 2–4 months (Stadlinger et al. 2009; Bressan et al. 2012; Botzenhart et al. 2015). Attainment of osseointegration and primary stability is essential for implant success. A high BIC is a prerequisite for implant stability and is vital in order to generate secondary stability (Brånemark, 1983; Albrektsson 2008).

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