Publication date: Available online 23 June 2017
Source:Annales de Dermatologie et de Vénéréologie
Author(s): C. Dubois, A.-L. Liegeon, C. Fabbro, F. Truchetet
IntroductionNeisseria meningitidis (NM) est une bactérie commensale présente dans la flore oropharyngée et responsable d'infections invasives. Plus rarement, des localisations génitales ont été décrites. Nous présentons deux cas d'urétrite aiguë à NM.ObservationsDeux hommes de 30 et 31 ans, dont l'un homosexuel séropositif pour le VIH, présentaient un écoulement urétral compatible avec le diagnostic d'urétrite aiguë. Les prélèvements urétraux identifiaient la présence de NM de sérogroupes B et C. L'un des antibiogrammes montrait une sensibilité intermédiaire à la pénicilline G et à l'amoxicilline.DiscussionLa présentation clinique des urétrites aiguës à NM est aspécifique, justifiant la réalisation de prélèvements urétraux devant toute urétrite aiguë. Les urétrites à NM sont peu fréquentes, affectant principalement les hommes ayant des relations sexuelles avec des hommes (HSH). Leur recrudescence s'expliquerait par celle des pratiques sexuelles orogénitales non protégées. L'émergence de résistances de NM impose la réalisation systématique d'un antibiogramme afin d'adapter les stratégies thérapeutiques et prophylactiques. Des cas d'infections invasives à méningocoques de sérogroupe C ont été recensés dans la population HSH avec l'hypothèse d'une porte d'entrée sexuelle. Aussi le Haut conseil de la santé publique recommande-t-il la vaccination contre le méningocoque de sérogroupe C dans cette population.BackgroundNeisseria meningitidis (NM) is a commensal bacteria present in the oropharyngeal flora that causes invasive infections. There have been rarer reports of presence in the genital region. Herein, we present two cases of acute NM urethritis.Patients and methodsTwo men aged 30 and 31years, one of whom is homosexual and seropositive for HIV infection, presented urethral discharge which was diagnosed as acute urethritis. The unit through samples indicated the presence of NM of serogroups B and C. One of the antibiotic sensitivity tests revealed intermediate susceptibility to penicillin G and to amoxicillin.DiscussionThe clinical presentation of acute NM urethritis is non-specific, because of which urethral samples should be taken wherever acute urethritis is suspected. NM urethritis is infrequent and primarily affects men who have sex with men (MSM). Its current increase is due to unprotected oral-genital sexual practices. Due to the emergence of resistance to NM, antibiotic susceptibility testing should be carried out routinely to ensure appropriate therapy and prophylaxis. Cases of invasive serogroup C meningococcal infections have been recorded within the MSM population with hypothetical sexual port of entry. Thus, the French High Public Health Authority recommends vaccination against meningitis C in this population.
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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Σάββατο 24 Ιουνίου 2017
Urétrite à Neisseria meningitidis : deux cas
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