Heart Regeneration 4.0: Matrix Medicine

Publication date: 10 July 2017
Source:Developmental Cell, Volume 42, Issue 1
Author(s): Elif Eroglu, Kenneth R. Chien
The heart has a markedly limited capacity for regeneration. Reporting in Nature, Bassat et al. (2017) and Morikawa et al. (2017) have uncovered a new mechanism of Yap inhibition by the dystrophin glycoprotein complex (DGC) that is released by the extracellular matrix protein Agrin in order to promote cardiac regeneration.

Teaser

The heart has a markedly limited capacity for regeneration. Reporting in Nature, Bassat et al. (2017) and Morikawa et al. (2017) have uncovered a new mechanism of Yap inhibition by the dystrophin glycoprotein complex (DGC) that is released by the extracellular matrix protein Agrin in order to promote cardiac regeneration.


http://ift.tt/2sZ7Tgm