Nuclear Pore Complexes: A Scaffold Regulating Developmental Transcription?

Publication date: Available online 19 July 2017
Source:Trends in Cell Biology
Author(s): Atsushi Satomura, Jason H. Brickner
Nuclear pore complexes (NPCs) have a conserved, but poorly understood, role in transcriptional regulation. Recently, in Developmental Cell, Raices et al. argued that tissue-specific nuclear pore proteins (Nups) act as scaffolds that recruit the transcription factor Mef2C to the NPC, promoting transcription of NPC-associated genes during muscle development.



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