Author's response

Our primary hopes with the publication of this review1 were 2-fold: (1) to add to the body of literature supporting the safety of subcutaneous aeroallergen immunotherapy and (2) to provide a template for allergists who might want to use cluster or rush schedules but have been dissuaded by historically high systemic reaction rates. We recognize that our retrospective analysis of more than 2.5 million injections was not designed to best determine why our systemic reaction rates were lower than those previously published.

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