Disseminated Mycobacterium avium intracellulare leading to protein-losing enteropathy in an elderly man with idiopathic CD4 lymphocytopenia

Idiopathic CD4 lymphocytopenia (ICL) is a clinical diagnosis in which CD4+ T lymphocytes constitute fewer than 300 cells/μL or fewer than 20% of total T cells without evidence of human immunodeficiency virus (HIV) or any defined immunodeficiency or therapy associated with decreased levels of CD4+ T cells.1 Mycobacterium is one of the most common opportunistic infections in ICL. We report on a unique case of a 64-year-old man with ICL who developed protein-losing enteropathy (PLE) secondary to disseminated Mycobacterium avium intracellulare (MAI) infection that resolved with successful treatment of the mycobacterium infection.

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