Multi-criterial patient positioning based on dose recalculation on scatter-corrected CBCT images

Publication date: Available online 12 October 2017
Source:Radiotherapy and Oncology
Author(s): Jan Hofmaier, Jonas Haehnle, Christopher Kurz, Guillaume Landry, Cornelius Maihoefer, Lars Schüttrumpf, Philipp Süss, Katrin Teichert, Matthias Söhn, Nadine Spahr, Christoph Brachmann, Florian Weiler, Christian Thieke, Karl-Heinz Küfer, Claus Belka, Katia Parodi, Florian Kamp
Background and purposeOur aim was to evaluate the feasibility and potential advantages of dose guided patient positioning based on dose recalculation on scatter corrected cone beam computed tomography (CBCT) image data.Material and methodsA scatter correction approach has been employed to enable dose calculations on CBCT images. A recently proposed tool for interactive multicriterial dose-guided patient positioning which uses interpolation between pre-calculated sample doses has been utilized. The workflow was retrospectively evaluated for two head and neck patients with a total of 39 CBCTs. Dose–volume histogram (DVH) parameters were compared to rigid image registration based isocenter corrections (clinical scenario).ResultsThe accuracy of the dose interpolation was found sufficient, facilitating the implementation of dose guided patient positioning. Compared to the clinical scenario, the mean dose to the parotid glands could be improved for 2 out of 5 fractions for the first patient while other parameters were preserved. For the second patient, the mean coverage over all fractions of the high dose PTV could be improved by 4%. For this patient, coverage improvements had to be traded against organ at risk (OAR) doses within their clinical tolerance limits.ConclusionsDose guided patient positioning using in-room CBCT data is feasible and offers increased control over target coverage and doses to OARs.



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