Characteristics of computed tomography perfusion parameters in non-small-cell-lung-cancer and its relationship to histology, size, stage an treatment response

Publication date: July–August 2018
Source:Clinical Imaging, Volume 50
Author(s): Carmen Trinidad López, Miguel Souto Bayarri, Roque Oca Pernas, Carlos Delgado Sánchez-Gracián, Maria González Vázquez, Antonio Vaamonde Liste, Gonzalo Tardáguila De La Fuente, Javier De La Fuente Aguado
ObjectivesTo analyze computed tomography perfusion (CTP) parameters in NSCLC.Materials and methodsProspective study, 152 patients with NSCLC. CTP parameters were correlated with histology, stage, size and response to conventional chemotherapy/radiotherapy.ResultsNeuroendocrine tumours presented higher BV (p 0.002). Negative correlation of PMB (p 0.003) and positive of MTT (p 0.046) with T stage was found. BF showed negative correlation with size. No differences were found with the RECIST levels of response to chemotherapy/radiotherapy.ConclusionsCTP parameters were highly variable. Neuroendocrine tumours presented higher BV and PMB values. Perfusion parameters do not differ depending on the stage and do not predict response to treatment.



http://ift.tt/2ka2L1P