Hypercoagulability and Vascular Disease

Publication date: Available online 1 December 2017
Source:Hematology/Oncology Clinics of North America
Author(s): Ali T. Taher, Maria Domenica Cappellini, Rayan Bou-Fakhredin, Daniel Coriu, Khaled M. Musallam

Teaser

The presence of a high incidence of thrombotic events, mainly in nontransfusion-dependent β-thalassemia syndromes, has led to the identification of a hypercoagulable state in thalassemia patients. This article highlights the mechanisms leading to hypercoagulability in thalassemia. It also discusses the clinical experience and available evidence on prevention and management approaches.


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