[Progress in diagnosis and treatment of radioactive iodine-refractory differentiated thyroid carcinoma].

[Progress in diagnosis and treatment of radioactive iodine-refractory differentiated thyroid carcinoma].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Dec 07;52(12):956-960

Authors: Zhao Z, Shen GH, Li YH, Zhou K, Cai HW

Abstract
The radioactive iodine-refractory differentiated thyroid carcinoma (RIR-DTC) is a complex process that involves multiple genetic changes and multiple signaling pathways.Radionuclide imaging, genomics and proteomics are effective to clarify the mechanism and helpful in clinical diagnosis and therapy.The treatment of RIR-DTC includes the removal of distant metastases, drug therapy, external radiotherapy and radiofrequency ablation.This review mainly focuses on the pathogenesis, diagnosis and treatment of RIR-DTC.

PMID: 29262462 [PubMed - in process]

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