Atypical Presentation of Radiation-Associated Breast Angiosarcoma: A Case Report and Review of Literature.

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Atypical Presentation of Radiation-Associated Breast Angiosarcoma: A Case Report and Review of Literature.

Am J Case Rep. 2017 Dec 18;18:1347-1350

Authors: Farran Y, Padilla O, Chambers K, Philipovskiy A, Nahleh Z

Abstract
BACKGROUND Radiation-associated breast angiosarcoma is a rare clinical entity that is thought to be increasing in incidence. CASE REPORT Here we present the case of a 67-year-old female with a history of left breast invasive ductal carcinoma who received breast conserving surgery and radiation therapy eight years ago. She then presented with a painless mild skin discoloration of the left breast that had been present for over one year. Mammograms and ultrasounds were normal. A punch biopsy and a subsequent excisional biopsy revealed the diagnosis of angiosarcoma. The patient was treated with mastectomy and had no subsequent recurrences. CONCLUSIONS The long-term clinical surveillance for all patients who receive breast conservation surgery is recommended and a high degree of suspicion should be exercised in view of potential atypical presentations of this disease.

PMID: 29249796 [PubMed - indexed for MEDLINE]

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