Intraoperative MRI-guided biopsy in the diagnosis of suprasellar Langerhans Cell Histiocytosis.

Intraoperative MRI-guided biopsy in the diagnosis of suprasellar Langerhans Cell Histiocytosis.

World Neurosurg. 2018 Jan 06;:

Authors: Carroll KT, Lochte BC, Chen JY, Snyder VS, Carter BS, Chen CC

Abstract
Magnetic resonance imaging (MRI)-guided biopsy is an emerging diagnostic technique that holds great promise for otherwise difficult to access neuroanatomy. Here we describe MRI-guided biopsy of a suprasellar lesion located posterior and superior to the pituitary stalk. The approach was successfully implemented in a 38-year-old woman who had developed progressive visual deterioration. Intra-operative MRI revealed the need for trajectory adjustment due to an unintended, minor deviation in the burr hole entry point, demonstrating the benefit of an MRI-guided approach. Langerhans cell histiocytosis (LCH) was diagnosed after biopsy, and the lesion regressed after cladribine treatment. Technical nuances of the case are reviewed in the context of the available literature.

PMID: 29317365 [PubMed - as supplied by publisher]

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