Pituitary carcinoid coexisting with systemic lupus erythematosus: A rare combination.

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Pituitary carcinoid coexisting with systemic lupus erythematosus: A rare combination.

Natl Med J India. 2016 Jul-Aug;29(4):209-211

Authors: Bhambhani A, Dugar M, Rao J, Prasad R

Abstract
Gastrointestinal carcinoids have occasionally been reported in patients with autoimmune diseases. We report a middle-aged woman who presented with episodic hypertension and a skin rash. Initial evaluation led to the diagnosis of systemic lupus erythematosus for which the patient was treated. Further investigations revealed the presence of a carcinoid tumour in the pituitary. Although gastrointestinal carcinoids associated with autoimmune diseases have been seen occasionally, to our knowledge, extragastric carcinoid coexisting with an auto- immune disorder has never been reported before. A better understanding of how inflammation induces cytological changes leading to development of a carcinoid from a cellular and molecular perspective could provide potential therapeutic strategies for preventing these lesions.

PMID: 28050998 [PubMed - indexed for MEDLINE]

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