Recurrent stroke in a patient of lung cancer without pulmonary mass: A case report.

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Recurrent stroke in a patient of lung cancer without pulmonary mass: A case report.

Medicine (Baltimore). 2018 Feb;97(5):e9815

Authors: Wang L, Xu Y, Tuo M, Zhang L, Zhang H, Wang J

Abstract
RATIONALE: Repeated occurring stroke in short intervals with hypercoagulability is unusual so in such cases the conventional vascular risk factors might not be the causes of stroke.
PATIENT CONCERNS: We have presented a case of 60-year-old male presenting with recurrent stroke due to thrombophilia.
DIAGNOSES: Lung cancer was detected by superficial lymph nodes ultrasound and further pathological examination.
INTERVENTIONS: The patient suffered a recurrent stroke and he had persistently high level of D-dimer which suggested the diagnosis of thrombophilia, thus, he was treated with low-molecular-weight heparin. Unfortunately, the treatment was not effective for the patient and he died before any other treatments could be administered.
OUTCOMES: Despite anticoagulant therapy, the patient suffered multiple episodes of stroke and ultimately died.
LESSONS: This case of recurrent stroke with coagulation disorders without evidence of cancer in imaging and blood test is rare. So in a stroke patient, we should consider malignancy or metastasis as a differential diagnosis as it may be the first manifestation of active cancer elsewhere.

PMID: 29384885 [PubMed - indexed for MEDLINE]

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