Salvage transoral laser microsurgery for recurrent glottic carcinoma after primary laser-assisted treatment: Analysis of prognostic factors.

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Salvage transoral laser microsurgery for recurrent glottic carcinoma after primary laser-assisted treatment: Analysis of prognostic factors.

Head Neck. 2016 Jul;38(7):1043-9

Authors: Lucioni M, Bertolin A, Lionello M, Giacomelli L, Rizzotto G, Marioni G

Abstract
BACKGROUND: Treatment for local glottic cancer recurrences after primary transoral laser microsurgery (TLM) has not been standardized.
METHODS: In 33 consecutive cases of salvage TLM after laser surgery for early glottic carcinoma failed, we retrospectively considered the potential clinicopathological prognostic factors in univariate statistical setting.
RESULTS: Patient age <65 years and pathological involvement of the deep margins were associated with a higher second recurrence rate and shorter disease-free survival.
CONCLUSION: The age of the patient and the pathological status of surgical margins after salvage TLM could be useful for planning a closer endoscopic/radiological follow-up in selected patients at high risk of recurrence. Other appropriately designed studies are needed to see if an open surgical approach should be considered for younger patients (<65 years old) with recurrent glottic carcinoma after primary TLM. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1043-1049, 2016.

PMID: 26969869 [PubMed - indexed for MEDLINE]

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