The clinical application of a silicate-based wound dressing (DermFactor®) for wound healing after anal surgery: A randomized study.

The clinical application of a silicate-based wound dressing (DermFactor®) for wound healing after anal surgery: A randomized study.

Int J Surg. 2018 Feb 23;:

Authors: Chen S, Huan Z, Zhang L, Chang J

Abstract
BACKGROUND: The object of the present study is to evaluate the feasibility of a silicate-based wound dressing (DermFactor®) in treating the wound of the patients after anorectal surgery.
MATERIALS AND METHODS: The present study included 328 patients who received anal surgery during the period from March 2013 to June 2015. The patients were randomized to 2 groups. The patients (n = 162) in the control group received conventional dressing therapy, while those in the observation group (n = 166) were treated with the combination of conventional dressing therapy and the use of a silicate-based wound dressing (DermFactor®). The wound healing outcomes of the two groups were observed and compared with each other by statistical analysis.
RESULTS: The average healing cycles in the observation group were 19.04 days for combined hemorrhoid patients, 23.72 days for anal fistula patients and 21.14 days for anal fissure patients, respectively, which were shorter than those in the control group (23.25 days for mixed hemorrhoid patients, 27.76 days for anal fistula patients and 24.32 days for fissure in ano patients, respectively). In addition, the observation group presented a significantly higher effective rate (80.4%) than the control group (70.4%).
CONCLUSION: Our data demonstrated that the wound after anorectal surgery could be more effectively treated by using silicate-containing DermFactor®.

PMID: 29481992 [PubMed - as supplied by publisher]

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