Colon Cancer: Inflammation-Associated Cancer.

Colon Cancer: Inflammation-Associated Cancer.

Surg Oncol Clin N Am. 2018 Apr;27(2):269-287

Authors: Shawki S, Ashburn J, Signs SA, Huang E

Abstract
Colitis-associated cancer is a relatively rare form of cancer with an unclear pathogenesis. Colitis-associated cancer serves as a prototype of inflammation-associated cancers. Advanced colonoscopic techniques are considered standard of care for surveillance in patients with long-standing colitis, especially those with other risk factors, including sclerosing cholangitis and a family history of colorectal cancer. When colitis-associated cancer is diagnosed, the standard operation involves total proctocolectomy. Restorative procedures and surveillance after colectomy require special considerations. In these contexts, new 3-dimensional human models may be used to usher in personalized medicine.

PMID: 29496089 [PubMed - in process]

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