Functional Electrical Stimulation-A new therapeutic approach to enhance exercise intensity in Chronic Obstructive Pulmonary Disease patients : a randomised controlled cross-over trial.

Publication date: Available online 7 March 2018
Source:Archives of Physical Medicine and Rehabilitation
Author(s): Clément Medrinal, Guillaume Prieur, Yann Combret, Aurora Robledo Quesada, David Debeaumont, Tristan Bonnevie, Francis Edouard Gravier, Elise Dupuis Lozeron, Jean Quieffin, Olivier Contal, Bouchra Lamia
ObjectiveTo evaluate the effect of quadriceps Functional Electrical Stimulation (FES)-Cycling on exertional VO2 compared with Placebo FES-cycling in patients with COPD.DesignA randomised, single-blind, placebo-controlled, cross-over trialSettingPulmonary Rehabilitation DepartmentParticipants23 consecutive patients with COPD GOLD stage 2, 3 or 4 (mean FEV1 : 1.4±0.4 L (50.3% pred)) who had recently begun a respiratory rehabilitation program.InterventionTwo consecutive 30-minute sessions were carried out at a constant load with active and placebo FES-Cycling.Main outcome measuresThe primary outcome was mean VO2 during the 30-minute exercise session. The secondary outcomes were respiratory gas exchange and hemodynamic parameters averaged over the 30-minute endurance session. Lactate values, dyspnea and perceived muscle fatigue were evaluated at the end of the sessions.ResultsFES-Cycling increased the physiological response more than the placebo, with a greater VO2 achieved of 36.6 (95% CI 8.9-64.3) mL/min (p=0.01). There was also a greater increase in lactate after FES-Cycling (+1.5 (95% CI 0.05 to 2.9) mmol/L; p=0.01). FES-Cycling did not change dyspnoea or muscle fatigue compared with the placebo condition.ConclusionFES-Cycling effectively increased exercise intensity in patients with COPD. Further studies should evaluate longer-term FES-Cycling rehabilitation programs.



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