Case Report: A Comparative Report on Intracranial Tumor-to-Tumor Metastasis and Collision Tumors.

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Case Report: A Comparative Report on Intracranial Tumor-to-Tumor Metastasis and Collision Tumors.

World Neurosurg. 2018 Apr 25;:

Authors: Syed S, Karambizi DI, Baker A, Groh DM, Toms SA

Abstract
BACKGROUND: The incidence of two distinct tumor types occupying the same anatomical location is rarely observed and may be accounted for by two separate mechanisms: Tumor to tumor metastasis and "collision" tumors where two adjacent tumors invade one another. These rare phenomena arise from distinct mechanisms, which may impact their preoperative recognition, surgical approach, and postoperative care. We will review two cases, highlighting their identification and perioperative management.
CASE DESCRIPTIONS: In case 1, a 71-year-old patient with history of sphenoid wing meningioma presented with headache, nausea, vomiting and was found to have a mass with meningioma and glioblastoma (GBM) characteristics. In case 2, a 61-year-old male with worsening dysmetria in the setting of unintentional weight loss, presented with multiple masses in the pelvis, abdomen, lung, and brain. The brain masses were classified as meningioma with intra-tumoral metastatic adenocarcinoma foci.
CONCLUSION: Preoperative recognition of collision tumor and tumor-to-tumor metastasis is imperative for surgical planning including selecting regions for tissue biopsy and goals of care. Meticulous evaluation of history and imaging, and thorough pathological analysis allows for effective diagnosis and optimal patient outcomes.

PMID: 29704691 [PubMed - as supplied by publisher]

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