Clinical Experience of Autologous Blood Transfusion in Neurosurgery: Prospective Study in Central India.

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Clinical Experience of Autologous Blood Transfusion in Neurosurgery: Prospective Study in Central India.

World Neurosurg. 2018 Apr 25;:

Authors: Patil H, Navakar D, Banabokade L, Garg N

Abstract
OBJECTIVE: The purpose of this study was to evaluate the benefits of intraoperative autologous blood transfusion in intracranial procedures and to conserve precious homologous blood due to shortage of donor and associated complications.
METHODS: This was a prospective study performed at Bansal hospital, Bhopal. Predetermined autologous blood was collected in a well labelled bag containing citrate phosphate dextrose adenine (CPDA) solution after induction of general anaesthesia. Then appropriate amount of crystalloid solution was transfused in to the body. All collected autologous blood was transfused back to the patient at the end of the surgery or during the surgery if excessive blood loss occurred. Demographic data, hemodynamic changes [mean arterial pressure (MAP), heart rate (HR)] before & after donation, complications, any additional homologous blood requirement were noted. Pre & post-operative hemoglobin & hematocrit values were compared.
RESULTS: Total 32 patients were included in this study. In our study mean age was 48.87 years; male female ratio was 1: 1.4. The mean amount of autologous blood collected was 461 ml and mean amount of blood loss during surgery was 1048 ml. In our study there was no statistically significant difference was found in MAP & HR before and after autologous blood collection (P > 0.05). When we compared pre & post-operative mean hemoglobin and hematocrit levels, there was statistically significant difference present (P < 0.05), this was due to maximum number of patients were meningiomas (15 out of 32). Additional homologous blood was required only in 25 % of cases (8 /32). Out of 8 patients 5 were again cases of deep seated meningiomas. No complication was observed during or after autologous blood collection.
CONCLUSION: Autologous blood transfusion is a safe, effective and affordable method of blood transfusion in patients undergoing intracranial surgery. Complications associated with homologous blood transfusion can be avoided with autologous blood transfusion.

PMID: 29704687 [PubMed - as supplied by publisher]

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