Publication date: Available online 5 April 2018
Source:Revue des Maladies Respiratoires
Author(s): H. Snene, A. Ben Mansour, S. Toujani, N. Ben Salah, M. Mjid, Y. Ouahchi, N. Mehiri, M. Beji, J. Cherif, B. Louzir
IntroductionLa tuberculose dans sa forme pseudotumorale est une entité rare. Quelle que soit sa localisation, elle peut simuler une néoplasie par sa présentation radiologique et/ou endoscopique. À travers ce travail, nous cherchons à mettre en exergue les difficultés diagnostiques de cette pathologie.MéthodesIl s'agit d'une étude rétrospective menée sur les dossiers de patients hospitalisés de 2003 à 2016, au service de pneumologie de l'hôpital La Rabta, pour tuberculose pseudotumorale thoracique.RésultatsDix-sept patients ont été colligés. L'âge médian était de 41 ans. La symptomatologie était dominée par la toux et le fléchissement de l'état général. Toutes les explorations radiologiques étaient pathologiques dont 10 cas de lésions suspectes. La fibroscopie bronchique avait montré des anomalies endobronchiques dans 11 cas. Le délai diagnostique global médian était de 97jours. Le diagnostic a été confirmé bactériologiquement dans cinq cas, histologiquement dans 14 cas et a été retenu sur des éléments de présomption dans un cas. L'évolution était favorable : 13 patients déclarés guéris et quatre patients sont en cours de traitement.ConclusionLe diagnostic positif de tuberculose pseudotumorale thoracique est difficile. Les prélèvements bactériologiques sont souvent négatifs. Ces difficultés sont à l'origine d'un important retard diagnostique et thérapeutique.IntroductionThe pseudotumorous form of tuberculosis is a rare entity. Whatever its location, it can simulate neoplasia by its radiological and/or endoscopic appearances. We highlight the diagnostic difficulties associated with this type of presentation.MethodsWe performed a retrospective study of inpatient records from 2003 to 2016 in the pneumology department of La Rabta Hospital to identify cases of thoracic tuberculous pseudo-tumor.ResultsSeventeen patients were identified. The median age was 41 years and their symptomatology was dominated by cough and general debility. All had abnormal radiology with 10 cases of suspect lesions. Fibre-optic bronchoscopy revealed endobronchial abnormalities in 11 cases. The median overall diagnostic delay was 97 days. The diagnosis was confirmed bacteriologically in five cases, histologically in 14 cases and based on clinical presumption in one case. The progression was favourable: 13 patients have been declared cured and four patients are still undergoing treatment.ConclusionMaking a positive diagnosis of thoracic tuberculous pseudotumour can be difficult, as bacteriological samples are often negative. This can lead to a significant delay in diagnosis and treatment.
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00306932607174
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