Background. We performed a review of published case studies of osteomyelitis associated with cat-scratch disease to consolidate existing information on clinical presentation, diagnostic tools, therapy, and outcome, as well as presenting a case of disseminated cat-scratch disease in a 12-year-old female with skull osteomyelitis and spleen involvement. Methods. A search for articles indexed in PubMed, Embase, and Google Scholar was performed with the search terms "Bartonella," "bone," "osteomyelitis," "osteolytic," and "cat-scratch disease" limited to the immunocompetent pediatric population and articles in English. Results. 51 cases were identified. The average age was 7.8 years with equal sex distribution. Fever (84.3%), often with a prolonged course (64.7%), and osteoarticular pain (88.2%) were the most common clinical findings. Lymphadenopathy was present in 64.7% of patients. Vertebral body was mainly involved (51.9%). MRI (50%) and bone scintigraphy (48.1%) were favored to confirm osteomyelitis, while serology was the preferred microbiological diagnostic. Various antibiotics were prescribed in combined or sequential regimens, with median duration of therapy of 23 days. About 12.5% of patients did not receive any treatment. Most patients had excellent prognosis; in particular, all patients not receiving any therapy showed complete recovery and no recurrence of symptoms. Conclusions. Bartonella henselae should be considered in differential diagnosis of localized lymphadentitis. Osteoarticular pain or limitation during cat-scratch disease in children should always be investigated for bone spreading. Owing to good prognosis, invasive procedures to obtain the bone material should be avoided. Serology is the gold standard diagnostic tool and MRI is the best radiographic technique to define bone and surrounding tissue involvement. Treatment represents a never-ending dilemma: surgical intervention or use of antibiotics is still controversial, and more studies are needed to define the best antimicrobial regimen.
https://ift.tt/2Gsc8be
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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Κυριακή 1 Απριλίου 2018
Osteomyelitis in Cat-Scratch Disease: A Never-Ending Dilemma—A Case Report and Literature Review
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- Comparative effect of photobiomodulation associate...
- Physical properties of hydrogel wound dressing and...
- ROS-induced autophagy reduces B16F10 melanoma cell...
- Two cases of unidentified acute compartment syndrome
- Limited incision harvest of the rectus abdominis m...
- Label-free sensitive luminescence biosensor for im...
- RE: “Deployment And Preterm Birth Among US Army So...
- 2017 Articles of the Year, Reviewers of the Year, ...
- Plasticity and biological diversity of myeloid der...
- How to cope with food allergy symptoms?
- Oral food challenge using different target doses a...
- 3D cell printing of in vitro stabilized skin model...
- Alternative Choices for Anterolateral Thigh Flaps ...
- Development of Targeted Muscle Reinnervation Model...
- Future Perspectives in the Management of Nerve Inj...
- Distal Nerve Transfer: Perspective of Reconstructi...
- Is the Oblique Branch a Preferable Vascular Pedicl...
- Dynamic Quantitative Assessment of Motor Axon Spro...
- Does Cigarette Smoking Harm Microsurgical Free Fla...
- Check the Record: Remote CT Scans for Breast Flap ...
- 3D cell printing of in vitro stabilized skin model...
- Gender comparisons of young adults’ eating behavio...
- “Successful non-invasive treatment of festoons.”
- Reply: Commetary on Primary Septal Cartilage Graft...
- A Hidden legacy of Dr.Ralph Millard, Jr.
- The use of fat grafting as antiestrogen vehicle fo...
- Muscle versus Fasciocutaneous Free Flaps in Lower ...
- Digital Natives Plastic Surgeons
- “Is There Value to Seeing a Transgender Fellowship...
- Does Orthognathic Surgery have a Significant Impac...
- “Treating Breast Conservation Therapy Defects with...
- Reply to Letter: Muscle versus fasciocutaneous fre...
- “Reply: Orthognathic Surgery Has a Significant Eff...
- “Analysis of Craniofacial Remodeling in the Aging ...
- “A New Microtia Reconstruction Method Using Delaye...
- “Analysis of Craniofacial Remodeling in the Aging ...
- “Pursuing Mirror Image Reconstruction in Unilatera...
- Book Review: Mastering Medical Photography of the ...
- Optimal Use of Surgical Drains: Evidence-Based Str...
- “Pathways to academic leadership in plastic surger...
- Wound Surface Area as a Risk Factor for Flap Compl...
- Evolution and Revolution of Perforator Flaps
- A retentive memory of tetrachloroethene respiratio...
- Dermal Fillers: The Risks to Eliminating Wrinkles
- Corrigendum to “Genetically defined variants of to...
- Serine protease inhibitors containing a Kunitz dom...
- Passive sentence comprehension difficulties and it...
- Effect of electronic cigarettes on human middle ear
- Acoustic Structure Quantification Versus Point She...
- Consistency and Generalizability of Dietary Patter...
- Exercise after Aortic Dissection: to Run or Not to...
- An intramural uterine fibroid became submucosal in...
- Cosmetics, Vol. 5, Pages 26: Rice Water: A Traditi...
- Elavl3 regulates neuronal polarity through the alt...
- 3-Tesla MRI-assisted detection of compression poin...
- Editorial Board
- EGFR is not amplified in ameloblastoma.
- Thyroid disorders and breast cancer risk in Asian ...
- Evaluation of superior concha bullosa by computed ...
- Preoperative radiologic patent blue localization f...
- The successful salvage of a thrombosed pancreatic ...
- Double cross finger flaps from the middle to the i...
- Renal cell metastasis to the thyroid gland: An eme...
- Intraabdominal actinomycosis resulting in a diffic...
- Trend in otolaryngological surgeries in an era of ...
- Subcortical sources dominate the neuroelectric aud...
- Pharyngocutaneous and tracheoesophageal fistula cl...
- Parent understanding of the risk of future limitat...
- Hemoptysis After CardioMEMS Implantation: Case Rep...
- Procalcitonin monitoring as a guide for antimicrob...
- Reductions in otitis and other respiratory tract i...
- Apigenin enhances the antitumor effects of cetuxim...
- Resistin upregulates MUC5AC/B mucin gene expressio...
- Salivary flow and xerostomia in patients with type...
- Out of balance: how a binaural coincidence detecti...
- Higher carbohydrate intake is associated with incr...
- Distinct profiles of TERT promoter mutations and t...
- A Retrospective Study to Compare the Use of the Me...
- Management of a Severe Cervicofacial Odontogenic I...
- Practice patterns and outcomes of chemoradiotherap...
- Click-evoked auditory brainstem responses and auti...
- Simultaneous targeting of EGFR, HER2 and HER4 by a...
- Incidence of head and neck cancer in children: A D...
- Transoral endoscopic thyroid surgery via the tri-v...
- Systematic review evaluating randomized controlled...
- Frontline Science: IL-18 primes murine NK cells fo...
- A Clinical Decision Support System Using Ultrasoun...
- In response to Double-blind, placebo-controlled st...
- A novel technique for tracheal reconstruction usin...
- Rendezvous endoscopic recanalization for complete ...
- A Review of Promising Natural Chemopreventive Agen...
- Engineered viral vectors for functional interrogat...
- Blue titania turns carbon dioxide into fuel
- Cheaper fuel cells with nanomaterials
- MRI gradient-echo phase contrast of the brain at u...
- Hypoparathyroidism Causing Seizures: When Epilepsy...
- Osteomyelitis in Cat-Scratch Disease: A Never-Endi...
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