A Mouse Ependymoma Model Provides Molecular Insights into Tumor Formation

Publication date: 26 June 2018
Source:Cell Reports, Volume 23, Issue 13
Author(s): Kristian W. Pajtler, Stefan M. Pfister
Ozawa et al. present a murine tumor model resembling the most frequent molecular group of human supratentorial ependymoma, ST-EPN-RELA. Their model shows RELA-fusion-based de novo ependymoma tumorigenesis in the forebrain derived from neural stem cells.

Teaser

Ozawa et al. present a murine tumor model resembling the most frequent molecular group of human supratentorial ependymoma, ST-EPN-RELA. Their model shows RELA-fusion-based de novo ependymoma tumorigenesis in the forebrain derived from neural stem cells.


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