Publication date: Available online 31 May 2018
Source:Molecular Immunology
Author(s): Thina Kailaivasan, Janet M. Davies
Grass pollens are amongst the most important aeroallergen sources world-wide triggering allergic rhinoconjunctivitis and asthma in sensitised patients. Much of what we know about the allergen components of grasses is informed by research on pollen of temperate (Pooideae) species that are abundant in the temperate climate zones. However, climate changes are altering the biogeographical distribution as well as timing and allergenicity of grass pollens. This provides an impetus for better understanding of the contribution of subtropical subfamilies of grasses to pollen allergy globally. Pollen of Chloridoideae (e.g. Cynodon dactylon; Bermuda grass) and Panicoideae (e.g. Paspalum notatum; Bahia grass or Sorghum halepense; Johnson grass) subfamilies are clinically important in subtropical zones of Australia, Asia, India, Africa, and America. These grasses differ ecologically and phylogenetically from temperate grasses and, importantly their allergen composition is qualitatively different. For example, subtropical grass pollens appear to lack the major group 5 grass pollen allergen family. In this review we summarize current knowledge of the epidemiology and immunology of subtropical Chloridoideae and Pancoideae pollen allergens, describe the biochemical characteristics of known isoforms and variants as well as properties and structures of subtropical pollen allergen components. Whilst only one subtropical allergen component; Cyn d 1 of Bermuda grass pollen, is available commercially for diagnostic use, in a natural purified form, a number of allergens of Panicoideae grass pollen; Zea m 1, Zea m 3 and Zea m 13 of maize, Pas n 1 and Pas n 13 of Bahia, as well as Sor h 1, Sor h 2, Sor h 13 and Sor h 23 of Johnson grass, have been discovered. Research effort is directed towards making available subtropical grass pollen allergen components as innovative treatment and diagnostic options that more specifically address the needs of patients from warmer regions of the globe.
https://ift.tt/2kGooaL
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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- Cuba Si. Cancer No.
- Editorial Board
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- Collagen secretion screening in Drosophila support...
- Radiological Study of the Ethmoidal Arteries in th...
- Alcohol consequences, not quantity, predict major ...
- Spanish adaptation of the Gambling Motives Questio...
- Exploring the role of positive metacognitions in e...
- Photo-excitable hybrid nanocomposites for image-gu...
- Blood-brain barrier shuttle peptides enhance AAV t...
- Editorial Board
- Contact dermatitis with concomitant contact urtica...
- The molecular allergology of subtropical grass pollen
- The molecular allergology of subtropical grass pollen
- Spectral Contrast Effects Produced by Competing Sp...
- Interplay between estrogen-related receptors and s...
- Stereotactic radiation therapy in the strategy of ...
- Biology, taxonomy, and IPM strategies of Bactrocer...
- Monitoring system for investigating the effect of ...
- Synthesis, Structure-Activity Relationship and Mol...
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