Metastasis of Ewing's Sarcoma to the Thyroid Gland: A Case Report

Publication date: Available online 11 July 2018

Source: International Journal of Pediatric Otorhinolaryngology

Author(s): Swathi Appachi, Joseph B. Meleca, Paul Krakovitz

Abstract

Ewing's sarcoma (ES) is an aggressive pediatric malignancy. We present a case of ES with thyroid metastasis. The patient was diagnosed with ES at age 8. Despite aggressive treatment, she suffered disease progression. Surveillance demonstrated a left thyroid lesion. This grew rapidly within 2 months, causing tracheal compression. She underwent hemi-thyroidectomy to prevent airway compromise. Due to her refractory ES, she was enrolled in the Vigil immunotherapy vaccine trial; thus, the specimen was used for vaccine development. This is the first reported case of skeletal ES with metastasis to the thyroid, requiring hemithyroidectomy to prevent airway compromise.

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