Dupilumab improves symptoms, quality of life, and productivity in uncontrolled persistent asthma

Asthma is a heterogeneous disease consisting of phenotypes defined, in part, by clinical parameters such as age of onset, presence of allergic features, degree of airway obstruction, obesity, gender, and smoking history.1-3 These characteristics may be associated with outcome and treatment response.3 Poor asthma control has been associated with increased risk of asthma exacerbations, asthma-related hospitalization,4,5 poor quality of life (QoL),6 adverse impact on productivity,7,8 and possibly, increased risk of mortality.

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