Forced oscillatory parameters in reversibility testing as predictors for chronic cough responsive to ICS/LABA

The cough guidelines recommend that asthma should always be considered as a potential etiology of chronic cough.1,2 The presence of airway hyperresponsiveness is consistent with, but not diagnostic of, cough due to mild asthma.A definitive diagnosis cannot be made until resolution of cough is achieved with specific therapy, including inhaled corticosteroid/long-acting β2 agonist (ICS/LABA) or ICS. Airway reversibility testing is often used to diagnose cough due to mild asthma; however, reversibility of forced expiratory volume in 1 second (FEV1) is smaller in mild asthma than in moderate asthma because baseline FEV1 values are normal or nearly normal in most patients with mild asthma.

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