Deceased brain dead donor liver transplantation and utilization in the United States: nighttime and weekend effects

Background Understanding factors that contribute to liver discards and non-usage is urgently needed to improve organ utilization. Methods With SRTR data, we studied a national cohort of all U.S. adult, deceased brain dead donor, isolated livers available for transplantation from 2003-2016, including organ-specific and system-wide factors that may affect organ procurement and discard rates. Results Of 73,686 available livers, 65,316 (88.64%) were recovered for transplant, of which 6,454 (9.88%) were ultimately discarded. Livers that were not procured or, upon recovery, discarded were more frequently from older, heavier, HCV+, and more comorbid donors (p

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