Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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! # Ola via Alexandros G.Sfakianakis on Inoreader

Η λίστα ιστολογίων μου

Πέμπτη 24 Ιανουαρίου 2019

OroFacial Medicine


Prevalence of oral mucosal disorders during pregnancy: A systematic review and meta‐analysis
Abstract Objective To assess the prevalence of oral mucosal disorders during pregnancy. Methods Observational studies were selected by two reviewers in a two‐phase process. Search strategies were applied at CINAHL, LILACS, LIVIVO, PubMed, Scopus, Web of Science, Google Scholar, Open Grey, and ProQuest. The risk of bias was assessed using the Joanna Briggs Institute's Critical Appraisal Checklist for Studies Reporting Prevalence Data. Synthesis of results was calculated by the software R...
Oral Pathology & Medicine
4h
Skeletal stability in orthognathic surgery with the surgery first approach: a systematic review
Publication date: Available online 23 January 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): D. Soverina, G. Gasparini, S. Pelo, P. Doneddu, M. Todaro, R. Boniello, C. Azzuni, C. Grippaudo, G. Saponaro, G. D'Amato, U. Garagiola, A. MoroAbstractThe surgery first approach (SFA) is a therapeutic strategy used in orthognathic surgery that is constantly evolving. With this approach, the pre-surgical orthodontic treatment can be eliminated, the maxilla and the mandible are...
Oral and Maxillofacial Surgery
5h
Pharyngeal airway space changes after maxillomandibular advancement: a five-year retrospective study
Publication date: Available online 23 January 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): P.M. Araújo, R.L.V. Osterne, A.C.G. de Souza Carvalho, N.O. Azevedo, R.F. Gondim, R.T. Gonçalves Filho, E. Sant'Ana, R.L.M. NogueiraAbstractThe aim of this study was to compare the alterations in three regions of the airway—nasopharynx, oropharynx, and hypopharynx—in relation to the area of the midsagittal plane, volume, and minimal axial area after maxillomandibular advancement...
Oral and Maxillofacial Surgery
5h
Assessment of metal sleeve-free 3D-printed implant surgical guides
Publication date: Available online 23 January 2019Source: Dental MaterialsAuthor(s): Kyung Chul Oh, Ji-Man Park, June-Sung Shim, Jee-Hwan Kim, Jong-Eun Kim, Jang-Hyun KimAbstractObjectivesThe aim of the present study was to investigate the adaptation and guide hole tolerance of metal sleeve-free computer-assisted implant surgical guides fabricated with 3D printers.MethodsAn implant surgical guide for full-guided implant placement was designed with a total of eight different guide holes. Ten implant...
Dental Materials
5h
Microvascular reconstruction and dental rehabilitation of benign severely atrophic jaws and defects of the alveolar ridge: our philosophy in 2019
We deal regularly with patients who present with severe atrophy of the jaws, compromised soft tissue, or penetrating defects of the alveolar ridge that are not the result of malignant disease. For these patients we use microvascular bony flaps together with dental implants and implant-supported prostheses. The purpose of this retrospective study was to present our current management and the lessons we have learned over a 16-year period while treating 86 patients for these indications with 87 microvascular...
Oral and Maxillofacial Surgery
15h
Pharyngeal airway space changes after maxillomandibular advancement: a five-year retrospective study
The aim of this study was to compare the alterations in three regions of the airway—nasopharynx, oropharynx, and hypopharynx—in relation to the area of the midsagittal plane, volume, and minimal axial area after maxillomandibular advancement (MMA) surgery. Thirty patients who had undergone MMA surgery were evaluated at four time points: preoperative (T0), immediately postoperative (T1), 1year postoperative (T2), and ≥5 years postoperative (T3). All measurements were performed using computed tomography,...
Oral & Maxillofacial Surgery
16h
Skeletal stability in orthognathic surgery with the surgery first approach: a systematic review
The surgery first approach (SFA) is a therapeutic strategy used in orthognathic surgery that is constantly evolving. With this approach, the pre-surgical orthodontic treatment can be eliminated, the maxilla and the mandible are surgically repositioned into the desired position, and the therapy is ended with a short orthodontic phase. Several studies have reported that the SFA is an acceptable approach, but postoperative stability is unclear. In this study, a systematic review on the SFA was performed.
Oral & Maxillofacial Surgery
16h
Predictive value of FHIT, p27, and pERK1/ERK2 in salivary gland carcinomas: a retrospective study
Abstract Objectives The aim of this study was to investigate the predictive value of the biomarkers FHIT, p27, and pERK1/ERK2 in salivary gland carcinomas. Material and methods Immunohistochemical staining of FHIT, p27, and pERK1/ERK2 of 265 patients with salivary gland carcinomas was conducted, and associations with clinico-histopathological data, overall...
Clinical Oral Investigations
18h
Fludroxycortide cream as an alternative therapy for actinic cheilitis
Abstract Objectives The objective of the study is to assess, by clinical follow-up, the efficacy of the dermatological cream Fludroxycortide 0.125 mg/g (Drenison®) in the treatment of actinic cheilitis (AC). Material and methods Twenty-three patients diagnosed with AC participated in the study. Fifteen were submitted to corticotherapy with Fludroxycortide,...
Clinical Oral Investigations
18h
Systemic comorbidities are associated with medication‐related osteonecrosis of the jaws: case‐control study
Abstract Objectives Medication‐related osteonecrosis of the jaws (MRONJ) is a serious condition developed in up to 15% of patients who take antiresorptive medications. Its underlying pathogenesis remains unclear. The association between systemic comorbidities and MRONJ was investigated. Subjects and Methods A case‐control study was conducted in Brisbane, Australia. Hospital records were used to identify 68 cases of MRONJ between January 2003‐ March 2017. Each case was individually matched...
Oral Diseases
20h
The role of autophagy in the pathogenesis of periodontal disease
Abstract Periodontal disease is a chronic inflammatory disease leading to destruction of periodontal tissues. As a local inflammation, periodontopathic bacterium, pro‐inflammatory mediators and local immune response play pivotal role in the progress of periodontal disease. Besides, cigarette smoke has long been associated with periodontal disease and tooth loss. Autophagy is an intracellular degradation process highly conserved from yeast to humans. As a lysosomal degradation pathway of self‐digestion,...
Oral Diseases
20h
Following in the footsteps of Hippocrates—interrelation between the incidence of odontogenic abscess and meteorological parameters
Abstract Objectives Although many physicians in daily practice assume a connection between odontogenic infections and meteorological parameters, this has not yet been scientifically proven. Therefore, the aim of the present study was to evaluate the incidence of odontogenic abscess (OA) in relation to outdoor temperature and atmospheric pressure. Patients and methods ...
Clinical Oral Investigations
20h
Scanning electron microscopy analysis of aligner fitting on anchorage attachments
Abstract Purpose The aims of the study were (1) to evaluate the fitting of three different aligners (Invisalign [Align Technology, Santa Clara, CA, USA], CA Clear Aligner [Scheu-Dental, Iserlohn, Germany] and F22 [Sweden&Martina, Due Carrare, Italy]) on anchorage attachments using scanning electron microscopy (SEM), and (2) to analyze the influence of 2 different types of resin used to build attachments on aligner fitting. ...
Latest Results for Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie
22h
Impact of breastfeeding and/or bottle-feeding on surgical wound dehiscence after cleft lip repair in infants: a systematic review
Publication date: Available online 23 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Eriko Matsunaka, Shingo Ueki, Kiyoko MakimotoSummaryBackgroundImmediately after cleft lip repair, breastfeeding and bottle-feeding are generally restricted to avoid placing tension on the surgical incision. However, no consensus about feeding methods after cleft lip repair has been reached. The objective of this systematic review was to examine the impact of breastfeeding and/or bottle-feeding...
Cranio-Maxillofacial Surgery
1d
An <em>in vitro</em> long-term study of cryopreserved umbilical cord blood-derived platelet-rich plasma containing growth factors—PDGF-BB, TGF-β, and VEGF
Publication date: Available online 22 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Kyoko Baba, Yasuharu Yamazaki, Yumiko Sone, Yoshika Sugimoto, Kazuno Moriyama, Takayuki Sugimoto, Kennichi Kumazawa, Yasuhito Shimakura, Akira TakedaSummaryPurposeUmbilical cord blood-derived platelet-rich plasma (UCB-PRP) containing growth factors has attracted attention as a biomaterial useful for regenerative medicine. The osteoblastic differentiation of umbilical cord-derived mesenchymal...
Cranio-Maxillofacial Surgery
1d
Analysis of the association of <em>IL4</em> polymorphisms with orthodontic mini-implant loss
Publication date: Available online 23 January 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): T.F. Lopes, C.M. Souza, A.M. Reichow, A.C. Melo, P.C. TrevilattoAbstractThe aim of this study was to investigate the association of clinical characteristics and IL4 tag single nucleotide polymorphisms (SNPs; rs2227284 and rs2243268) with orthodontic mini-implant (MI) failure. The sample included 135 subjects of both sexes, mean age 48.7 ± 10 years (range 20–76 years): 104 in...
Oral and Maxillofacial Surgery
1d
Implant fracture failure rate and potential associated risk indicators: An up‐to 12‐year retrospective study of implants in 5124 patients
Abstract Objectives This study investigated fracture rates and risk indicators for fractures in internal connection dental implants. Material and Methods We performed a retrospective analysis of 19,006 internal connection implants used in fixed restoration in 5,124 patients (4,570 males, 554 females) at the Dental Hospital of Veterans Health Service Medical Center between 2006 and 2015. Patients were followed through June 2018 (0.03–12.39 years post‐installation). Clinical factors (age,...
Clinical Oral Implants Research
1d
Assessment of Interleukin – 18 gene polymorphism and serum levels in Oral Lichen Planus in an Indian population
Abstract Background Oral Lichen Planus (OLP) is a chronic, inflammatory disease with uncertain aetiology. The aim of this study was to assess Interleukin‐18 (IL‐18) gene polymorphism and serum levels in OLP cases of Indian origin and to compare them with a control population of similar background. Methods Assessment of single nucleotide polymorphisms (SNPs) of IL‐18 gene at promoter regions 137(G/C) and 607(C/A) was done in 70 OLP cases and 70 healthy controls using sequence specific primer‐polymerase...
Oral Pathology & Medicine
1d
N-acetyl cysteine versus chlorhexidine mouthwashes in prevention and treatment of experimental gingivitis: a randomized, triple-blind, placebo-controlled clinical trial
Abstract Objectives To compare the efficacy of N-acetyl cysteine (NAC) mouthwash with chlorhexidine (CHX) in prevention and treatment of experimental gingivitis Materials and methods Sixty subjects were assigned randomly and blindly into one of three equal groups: NAC, CHX, or placebo group. The study was conducted in two stages: preventive and treatment...
Clinical Oral Investigations
1d
Investigation into the accuracy and measurement methods of sequential 3D dental scan alignment
Publication date: Available online 23 January 2019Source: Dental MaterialsAuthor(s): Saoirse O'Toole, Cecilie Osnes, David Bartlett, Andrew KeelingAbstractObjectivesAlignment procedures have yet to be standardised and may influence the measurement outcome. This investigation assessed the accuracy of commonly used alignment techniques and their impact on measurement metrics.MethodsDatasets of 10 natural molar teeth were created with a structured-light model-scanner (Rexcan DS2, Europac 3D, Crewe)....
Dental Materials
1d
A novel histopathological scoring system for patients with oral squamous cell carcinoma
Abstract Objectives Tumor invasion into blood and/or lymphatic vessels, perineural invasion, and histopathological grading are evaluated to assess the biological aggressiveness of oral squamous cell carcinoma (OSCC). We aim to assess the prognostic impact of a novel scoring system, based upon the aforementioned histological parameters. Materials and methods ...
Clinical Oral Investigations
1d
Analysis of the association of IL4 polymorphisms with orthodontic mini-implant loss
The aim of this study was to investigate the association of clinical characteristics and IL4 tag single nucleotide polymorphisms (SNPs; rs2227284 and rs2243268) with orthodontic mini-implant (MI) failure. The sample included 135 subjects of both sexes, mean age 48.7±10years (range 20–76years): 104 in the control group (patients without any MI loss) and 31 in the study group (patients presenting ≥1 MI loss). Genotypes were determined by real-time PCR. Bivariate and multivariate analyses were performed...
Oral & Maxillofacial Surgery
1d
Influence of Porphyromonas gingivalis in gut microbiota of streptozotocin‐induced diabetic mice
Abstract Objectives Increasing evidence suggests that periodontitis can exacerbate diabetes, and gut bacterial dysbiosis appears to be linked with the diabetic condition. The present study examined the effects of oral administration of the periodontopathic bacterium, Porphyromonas gingivalis, on the gut microbiota and systemic conditions in streptozotocin‐induced diabetic mice. Materials and Methods Diabetes was induced by streptozotocin injection in C57BL/6J male mice (STZ). STZ and wild‐type...
Oral Diseases
1d
Overexpression of EphrinB2 in Stem Cells from Apical Papilla Accelerates Angiogenesis
Abstracts Objectives we aimed to accelerate angiogenesis in pulp regeneration by modulating ephrinB2 expression in stem cells from apical papilla (SCAPs). Materials and Methods SCAPs were transducted with ephrinB2‐lentiviral expression vector in experimental group (ephrinB2‐SCAPs) and green fluorescent protein (GFP‐SCAPs) in control group. The transduction efficiency was confirmed by real‐time PCR and western blot assays. MTT assay was performed to detect the proliferative capacity of SCAPs...
Oral Diseases
1d
Inhibition of secondary caries <em>in vitro</em> by addition of chlorhexidine to adhesive components
Publication date: Available online 22 January 2019Source: Dental MaterialsAuthor(s): Christina Boutsiouki, Roland Frankenberger, Susanne Lücker, Norbert KrämerAbstractObjectiveTo investigate secondary caries inhibition after dentine pre-treatment with 2% CHX, experimental addition of CHX in primer and adhesive of a 3-step adhesive system, and industrial addition od CHX in a 2-step adhesive system.Materials and methodSixty Class-V cavities were restored according to the adhesive protocol (n = 12):...
Dental Materials
2d
Hydrophobicity of graphene as a driving force for inhibiting biofilm formation of pathogenic bacteria and fungi
Publication date: Available online 21 January 2019Source: Dental MaterialsAuthor(s): Shruti Vidhawan Agarwalla, Kassapa Ellepola, Mariana Caldeira Ferraz da Costa, Guilhermino José Macêdo Fechine, Julien Luc Paul Morin, A.H. Castro Neto, Chaminda Jayampath Seneviratne, Vinicius RosaAbstractObjectiveTo evaluate the surface and wettability characteristics and the microbial biofilm interaction of graphene coating on titanium.MethodsGraphene was deposited on titanium (Control) via a liquid-free technique....
Dental Materials
2d
Combining Platelet Rich Fibrin With Different Bone Graft Materials: An Experimental Study On The Histopathological And Immunohistochemical Aspects Of Bone Healing
Publication date: Available online 22 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Fatih Karayürek, Ela Tules Kadiroğlu, Yusuf Nergis, Neslihan Coşkun Akçay, Selçuk Tunik, Berna Ersöz Kanay, Ersin UysalAbstractAimThe current study was based on the hypothesis that the use of PRF with bone graft materials might increase bone regeneration and focus on the histopathological and immunohistochemical aspects following application of PRF with autogenous graft, xenograft and B-TCP...
Cranio-Maxillofacial Surgery
2d
The preventive effect of decellularized pericardial patch against Frey's syndrome following the superficial parotidectomy
Publication date: Available online 22 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Chengyong Wang, Dong Wu, Chuanqing Mao, Meng Lu, Zhiyu Cai, Yongzhen Lai, Weihui ChenSummaryPurposeThis study aimed to investigate the feasibility of adopting the ThormalGEN surgical patch (a porcine decellularized pericardial patch) in the superficial parotidectomy to prevent postoperative Frey's syndrome in patients with benign parotid tumor.Materials and MethodsA total of 59 patients with...
Cranio-Maxillofacial Surgery
2d
Examination of <em>OPG</em>, <em>RANK</em>, <em>RANKL</em> and <em>HIF1A</em> polymorphisms in temporomandibular joint ankylosis patients
Publication date: Available online 21 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Paola Fernanda Cotait de Lucas Corso, Michelle Nascimento Meger, Igor Bassi Ferreira Petean, Juliana Feltrin de Souza, João Armando Brancher, Lea Assed Bezerra da Silva, Nelson Luis Barbosa Rebelatto, Leandro Eduardo Kluppel, Manoel Damião Sousa-Neto, Erika Calvano Küchler, Rafaela ScariotSummaryPurposeTo evaluate the association between polymorphisms in genes that regulate bone metabolism,...
Cranio-Maxillofacial Surgery
2d
Comparative evaluation of different fixation techniques for sagittal split ramus osteotomy in 10 mm advancements. Part two: finite element analysis
Publication date: Available online 21 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Eder Alberto Sigua-Rodriguez, Ricardo Armini Caldas, Douglas Rangel Goulart, Paulo Hemerson de Moraes, Sergio Olate, Valentim Adelino Ricardo Barão, Jose Ricardo de Albergaria-BarbosaAbstractPurposeTo evaluate three rigid, stable fixation methods for sagittal split ramus osteotomy (SSRO), using finite element analysis. The hypothesis is that a customized miniplate presents better stress concentration...
Cranio-Maxillofacial Surgery
2d
Comprehensive assessment of tranexamic acid during orthognathic surgery: a systematic review and meta-analysis of randomized, controlled trials
Publication date: Available online 21 January 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Haoming Zhao, Shaopeng Liu, Zuping Wu, Huaqiang Zhao, Chuan MaAbstractThe objective of this study was to comprehensively assess the use of tranexamic acid (TXA) during orthognathic surgery. A systematic review and meta-analysis of randomized controlled trials addressing these issues were carried out. Three electronic databases, included PubMed, Web of Science, and Cochrane Library, were searched...
Cranio-Maxillofacial Surgery
2d
Azithromycin and Erythromycin susceptibility and macrolide resistance genes in Prevotella from patients with periodontal disease
Abstract Objectives To study oral Prevotella spp. isolated from patients with chronic periodontitis, to determine their susceptibility to azithromycin and erythromycin and to screen the presence of macrolide resistance genes therein. Material and Methods Isolates with a Prevotella‐like morphology were obtained from subgingival samples of 52 patients with chronic periodontitis. Each isolate was identified to the species level by sequencing of the 16S rRNA gene. In 100 Prevotella spp. isolates,...
Oral Diseases
2d
Clinical Evaluation of Full‐arch Screw‐Retained Implant‐Supported Fixed Prostheses and Full‐arch Telescopic‐Retained Implant‐Supported Fixed Prostheses: A 5–12 Year Follow‐up Retrospective Study
Abstract Objective To assess the prostheses and implants survival rate and peri‐implantitis rate in edentulous patients treated with full‐arch screw‐retained implant‐supported fixed dental prostheses (FSIFDPs) and full‐arch telescopic‐retained implant‐supported fixed dental prostheses (FTIFDPs) over an observation period of at least 5 years. Materials and Methods From 2004 to 2012, 696 implants were inserted into 78 patients with 102 prostheses. The FSIFDP group comprised 31 patients (37...
Clinical Oral Implants Research
2d
Maxillary osteotomy complications in piezoelectric surgery compared to conventional surgical techniques: a systematic review
Publication date: Available online 21 January 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): C. Thereza-Bussolaro, J. Galván Galván, C. Pachêco-Pereira, C. Flores-MirAbstractA systematic review was conducted to investigate the available evidence on maxillary complications related to piezoelectric and conventional surgery. Seven databases were searched. A total of 996 maxillary osteotomies were analysed, 864 performed with conventional tools and 132 with a piezoelectric...
Oral and Maxillofacial Surgery
2d
Maxillary osteotomy complications in piezoelectric surgery compared to conventional surgical techniques: a systematic review
A systematic review was conducted to investigate the available evidence on maxillary complications related to piezoelectric and conventional surgery. Seven databases were searched. A total of 996 maxillary osteotomies were analysed, 864 performed with conventional tools and 132 with a piezoelectric device. One hundred and fifty-six complication events were reported. The complications, in descending order of overall prevalence, were as follows: neurosensory disturbance (64.7%), haemorrhage (8.3%),...
Oral & Maxillofacial Surgery
2d
Effect of antiangiogenic targeted chemotherapy on the osseointegration of titanium implants in rabbits
Patients with cancer have recently been treated with more advanced targeted chemotherapies that have greater specificity towards the cancer cells and fewer side effects. However, the periods of treatment take longer than those of traditional cytotoxic treatments. The aim of this study was to examine the effect of antiangiogenic targeted chemotherapy on the osseointegration of titanium implants. Fourteen white New Zealand rabbits were allocated randomly into two groups of seven: the placebo control...
Oral and Maxillofacial Surgery
2d
World Workshop on Oral Medicine VII: Biomarkers predicting lymphoma in the salivary glands of patients with Sjögren's syndrome. A systematic review
Abstract Objective To conduct a systematic review of studies exploring potential biomarkers for development, course and efficacy of treatment of lymphomas in salivary glands of patients with Sjögren's syndrome. Material and Methods Eligible studies were identified through a comprehensive search of two databases, i.e. PubMed and EMBASE. Quality of included articles was assessed with the 'Quality In Prognosis Studies' (QUIPS) tool. The 'CHecklist for critical Appraisal and data extraction...
Oral Diseases
2d
Atraumatic restorative treatment—ART in early childhood caries in babies: 4 years of randomized clinical trial
Abstract Objective To assess the effectiveness of atraumatic restorative treatment (ART) performed 4 years ago in babies suffering from early childhood caries (ECC), and to compare the clinical performance of ART atraumatic restorations performed with two different high-viscosity glass ionomer cements (GIC). Materials and methods This was a longitudinal follow-up...
Clinical Oral Investigations
2d
Changes in proinflammatory gene expression in human whole blood after contact with UV-conditioned implant surfaces
Abstract Objectives The aim of this in vitro study was to assess changes in the gene expression of proinflammatory cytokines in human whole blood after contact with titanium implant surfaces conditioned by UV light. To this end, expression levels of proinflammatory cytokines were analyzed in vitro in human whole blood. Materials and methods Dental implants...
Clinical Oral Investigations
3d

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