Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
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alsfakia@gmail.com

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Παρασκευή 22 Φεβρουαρίου 2019

Inflammatory dietary pattern and incident psoriasis, psoriatic arthritis, and atopic dermatitis in women: a cohort study

Publication date: Available online 21 February 2019

Source: Journal of the American Academy of Dermatology

Author(s): Alanna C. Bridgman, Abrar Qureshi, Tricia Li, Fred K. Tabung, Eunyoung Cho, Aaron M. Drucker

Abstract
Background

Diet is a modulator of inflammation and may impact inflammatory skin diseases.

Objective

To assess the relationship between pro-inflammatory dietary patterns and incident psoriasis, psoriatic arthritis (PsA), and atopic dermatitis (AD).

Methods

We conducted cohort studies among women in the Nurses' Health Study II. The empirical dietary inflammatory pattern (EDIP) score was calculated at baseline and every four years. Incident psoriasis, PsA, and AD were assessed by validated self-report. We used multivariable-adjusted Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between EDIP quintiles and risk of psoriasis, PsA and AD.

Results

We had 85,185 participants in the psoriasis analysis and 63,443 in the AD analysis. There were 1,432 cases of psoriasis, 262 cases of PsA and 403 cases of AD. Pro-inflammatory dietary patterns were not associated with risk of the outcomes in multivariable models (all P-trend > 0.05). HRs comparing the highest to the lowest EDIP quintile were 0.99 (95% CI 0.83 – 1.18) for psoriasis, 1.22 (0.81 – 1.83) for PsA and 0.96 (0.69 – 1.34) for AD.

Limitations

Recall and self-report.

Conclusions

Our findings do not support dietary inflammatory potential as a risk factor for psoriasis, PsA or AD.



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