Utility of Pediatric Allergic Disease Quality of Life Questionnaire for childhood eczema

Abstract

Aim

It is important to objectively evaluate quality of life (QoL) impairment in atopic diseases in children. This study aims to investigate the utility of a Pediatric Allergic Disease Quality of Life Questionnaire (PADQLQ) in children with eczema.

Methods

PADQLQ, Patient‐Oriented Eczema Measure (POEM, a short‐term subjective‐symptom score), Nottingham Eczema Severity Score (NESS, a long‐term subjective‐symptom score), Children Dermatology Life Quality Index (CDLQI, a short‐term subjective‐symptom score) were compared and correlations evaluated.

Results

PADQLQ, POEM, NESS, CDLQI correlated well with each other (n=132 sets; spearman's correlations rho =0·48‐0·70, p<0·001). Bland Altman Plot showed a reasonably good agreement between CDLQI and PADQLQ. PADQLQ showed symptoms of asthma, allergic conjunctivitis and allergic rhinitis were present in 20‐30%, 45‐71%, and 58‐67%, respectively. Nevertheless, there was no association of eczema symptomatology by POEM or NESS with the severity of other allergic diseases.

Conclusion

PADQLQ correlates well with AD‐specific severity and QoL scores and reflects all allergic symptoms that holistically influence QoL in children with AD. PADQLQ is hence a composite severity score in terms of clinical symptomatology and QoL impairment for AD.

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