Publication date: Available online 5 April 2019Source: Allergology InternationalAuthor(s): Tomokazu Matsuoka, Satoshi Igarashi, Yuumi Kuroda, Chiharu Fukano, Kensuke Natsui, Katsuyo Doi-Ohashi, Keisuke Masuyama
Sat Apr 06, 2019 16:12
Publication date: Available online 4 April 2019Source: Allergology InternationalAuthor(s): Emi Nakauchi, Takeshi Fukumoto, Satoru Takahashi, Nobuyuki Horita, Masahiro Oka, Chikako Nishigori
Fri Apr 05, 2019 14:31
AbstractOccupational exposure to foods is responsible for up to 25% of cases of occupational asthma and rhinitis. Animal and vegetable high‐molecular weight proteins present in aerosolized foods during food processing, additives, preservatives, antioxidants and food contaminants are the main inhalant allergen sources. Most agents typically cause IgE‐mediated allergic reactions, causing a distinct form of food allergy (Class 3 food allergy). The allergenicity of a food protein, allergen exposure...
Sat Apr 06, 2019 21:58
AbstractAllergen‐specific immunotherapy (AIT) is the only disease‐modifying and curative treatment for allergic diseases. While in selected indications such as Hymenoptera venom allergy the curative success of AIT is impressingly high, in other disease manifestations it only reduces the symptoms to a certain extend in a fraction of patients. Key problems leading to a reduced efficacy of AIT seem to partly depend on local inflammatory processes that are not only causing side‐effects, but additionally...
Sat Apr 06, 2019 19:59
AbstractIndustrial sensitizing agents (allergens) in living and working environments play an important role in eliciting type I allergic disorders including asthma and allergic rhinitis. Successful management of allergic diseases necessitates identifying their specific causes (i.e. identify the causative agent(s) and the route of contact to allergen: airborne, or skin contact) to avoid further exposure. Identification of sensitization by a sensitive and validated measurement of specific‐IgE...
Sat Apr 06, 2019 19:59
AbstractInflammation, structural and functional abnormalities within the airways are key features of asthma. Although these processes are well‐documented, their expression varies across the heterogeneous spectrum of asthma. Type 2 inflammatory responses are characterized by increased levels of eosinophils, FeNO and type 2 cytokines in blood and/or airways. Presently, type 2 asthma is the best‐defined endotype, typically found in patients with allergic asthma, but surprisingly also in non‐allergic...
Sat Apr 06, 2019 17:13
Publication date: Available online 6 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Mark W. Tenn, Lisa M. Steacy, Daniel E. Adams, Terry J. Walker, Anne K. Ellis
Sat Apr 06, 2019 12:18
Publication date: Available online 6 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Jialing Jiang, Joel Gallagher, Jolanta Szkodon, Maaria Syed, Karina Gobin, Ruchi Gupta, Lucy Bilaver
Sat Apr 06, 2019 12:18
Publication date: Available online 5 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Rachna R. Dave, Catherine M. Hammond, Charles W. Stewart, D.Betty Lew
Sat Apr 06, 2019 12:18
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Debajyoti Ghosh, Jonathan Bernstein
Fri Apr 05, 2019 13:23
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Merin Kuruvilla, Meera Patrawala, Joshua M. Levy, Jennifer Shih, Frances E. Lee
Fri Apr 05, 2019 13:23
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Patrick M. Brunner
Fri Apr 05, 2019 13:23
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Ganesa Wegienka, Alexandra Sitarik, Albert M. Levin, Edward M. Zoratti, Dennis Ownby, Christine Cole Johnson, Suzanne Havstad
Fri Apr 05, 2019 13:23
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Michelle Lai, Scott H. Sicherer
Fri Apr 05, 2019 13:23
Publication date: Available online 6 April 2019Source: Autoimmunity ReviewsAuthor(s): Renaud Felten, Florence Scher, Jean Sibilia, Jacques-Eric Gottenberg, Laurent ArnaudAbstractTo date, no immunomodulatory drug has proved efficacious in primary Sjögren's syndrome (pSS). In pSS, difficulties in drug efficacy assessment is related to the large spectrum of clinical involvements (glandular/extraglandular involvement), to the lack of correlation between symptoms of dryness and glandular function assessed...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Aristo Vojdani
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Xiuhua Wu, Yu Liu, Wei Wei, Ming-Lin LiuAbstractSystemic vasculitis is diverse group of autoimmune disorders which are characterized by inflammation of blood vessel walls with deep aching and burning pain. Their underlying etiology and pathophysiology still remain poorly understood. Extracellular vesicles (EVs), including exosomes, microvesicles (MVs), and apoptotic bodies, are membrane vesicular structures that...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Qiuming Yao, Zhenyu Song, Bin Wang, Jin-an Zhang, Kaida Mu
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Piercarlo Sarzi-Puttini, Angela Ceribelli, Daniela Marotto, Alberto Batticciotto, Fabiola AtzeniAbstractThe development of biologics and small oral molecules has recently changed the scenario of pharmacologic treatment of systemic rheumatic diseases and it has become a real revolution. These drugs have innovative mechanisms of action, based on the inhibition of specific molecular or cellular targets directly involved...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Rafael Giovani Missé, Isabela Bruna Pires Borges, Samuel Katsuyuki Shinjo
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Ioannis Parodis, Lara Dani, Antonella Notarnicola, Git Martenhed, Pontus Fernström, Alexios Matikas, Oscar P.B. WiklanderAbstractBackgroundFebrile neutropenia is generally recognised as a complication of myelosuppressive chemotherapy. Recombinant human granulocyte colony stimulating factor (G-CSF) is commonly used as primary or secondary prophylaxis to reduce the degree and duration of neutropenia in patients at...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Mohamed Jahromi, Fahd Al-Mulla, Ebaa Al-Ozairi
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Nathan Peiffer-Smadja, Fanny Domont, David Saadoun, Patrice CacoubAbstractRecurrent pericarditis is a frequent and troublesome complication of acute pericarditis. Aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine are the mainstay of therapy but few data is available on second-line treatment. We retrospectively analyzed 13 patients, 7 females (54%), median age 40 years, with a median of 4 (IQR...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Chan-Na Zhao, Zhiwei Xu, Guo-Cui Wu, Yan-Mei Mao, Li-Na Liu, Qian-Wu, Yi-Lin Dan, Sha-Sha Tao, Qin Zhang, Napoleon Bellua Sam, Yin-Guang Fan, Yan-Feng Zou, Dong-Qing Ye, Hai-Feng PanAbstractAutoimmune diseases (ADs) are a broad spectrum of disorders featured by the body's immune responses being directed against its own tissues, resulting in prolonged inflammation and subsequent tissue damage. Recently, the exposure...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): M. Lucia Sur, Loredana Dascăl, Genel Sur, Daniel G. Sur, Emanuela Floca, Cornel Aldea, Iulia Lupan, Gabriel Samasca
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Anupama Karnam, Emmanuel Stephen-Victor, Mrinmoy Das, Laurent Magy, Jean-Michel Vallat, Francis Bolgert, Etienne Simon-Loriere, Srini V. Kaveri, Anavaj Sakuntabhai, Jagadeesh Bayry
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Amir Dagan, Pnina Langevitz, Yehuda Shoenfeld, Ora ShovmanAbstractBackgroundApproximately 5% of idiopathic recurrent pericarditis (IRP) patients are refractory or intolerant to NSAIDs, Colchicine and corticosteroids. The empiric treatment approach for these patients includes immunosuppression with Azathioprine (AZA) or immunomodulation with intravenous human immunoglobulin (IVIG). We assessed the efficacy and safety...
Sat Apr 06, 2019 16:43
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Maria Sole Chimenti, Francesco Caso, Stefano Alivernini, Erica De Martino, Luisa Costa, Barbara Tolusso, Paola Triggianese, Paola Conigliaro, Elisa Gremese, Raffaele Scarpa, Roberto PerriconeAbstractPsoriatic arthritis (PsA) is a chronic inflammatory arthritis that may be present in near 30% of patients affected by psoriasis (PsO), clinically characterized by inflammation of periarticular (e.g., enthesis) and articular...
Sat Apr 06, 2019 16:43
No abstract available
Thu Apr 04, 2019 03:00
BackgroundEosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus, producing failure to thrive in infants and dysphagia with food impaction in older children and adults. Although most people with EoE manifest atopic/allergic disease, the specific allergens to which immunoglobulin E (IgE) is directed, if any, have not yet been characterized.MethodsMucosal brush biopsy (MBB) and solid tissue biopsy (STB) specimens were prospectively obtained from 25 individuals with dysphagia...
Fri Apr 05, 2019 11:24
R. Jimenez-Saiz, Y. Ellenbogen and K. Bruton et al. developed a method to identify bona fide IgE+ MBCs in humans, demonstrated their extreme rarity in circulation and cautioned against the clinical utility of their assessment.
Fri Apr 05, 2019 03:00
Both prenatal and postnatal exposures to PM2.5 were associated with the later development of asthma. The vulnerable time windows might be within early- and mid-gestation and the first year after birth.
Fri Apr 05, 2019 03:00
Fri Apr 05, 2019 03:00
Publication date: Available online 6 April 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Erinn S. Kellner, Christa Krupski, Hye Sun Kuehn, Sergio D. Rosenzweig, Nao Yoshida, Seiji Kojima, David Boutbol, Sylvain Latour, Vincent Barlogis, Claire Galambrun, Asbjørg Stray-Pedersen, Hans Christian Erichsen, Rebecca A. Marsh
Sun Apr 07, 2019 15:33
Publication date: Available online 5 April 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Rodrigo Jiménez-Saiz, Yosef Ellenbogen, Kelly Bruton, Paul Spill, Doron D. Sommer, Hermenio Lima, Susan Waserman, Sarita U. Patil, Wayne G. Shreffler, Manel Jordana
Sat Apr 06, 2019 13:37
Publication date: Available online 5 April 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Emma Guttman-Yassky, Lisa Zhou, James KruegerAbstractSkin is replete with immune-competent cells that modulate signaling pathways to maintain a salubrious immunogenic/tolerogenic balance. This fertile immune environment plays a significant role in the development of allergic responses and sensitivities, but the mechanisms underlying these pathways have been underappreciated and underutilized...
Fri Apr 05, 2019 16:40
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