Cancers, Vol. 11, Pages 533: The Interplay of Autophagy and Tumor Microenvironment in Colorectal Cancer—Ways of Enhancing Immunotherapy Action Cancers doi: 10.3390/cancers11040533 Authors: Evangelos Koustas Panagiotis Sarantis Georgia Kyriakopoulou Athanasios G. Papavassiliou Michalis V. Karamouzis Autophagy as a primary homeostatic and catabolic process is responsible for the degradation and recycling of proteins and cellular components. The mechanism of autophagy has a...
Abstract Purpose Lymphopenia in patients with glioblastoma (GBM) is related to treatment as well as disease progression. This retrospective study investigated the prevalence, influencing factors, recoverability, and clinical significance of lymphopenia in GBM patients treated with concomitant chemoradiotherapy (CCRT). Patients and methods A total of 219 patients...
Abstract Osteosarcoma (OS) is an aggressive malignant tumor of the bones. Our study intended to identify and analyze potential pathogenic genes and upstream regulators for OS. We performed an integrated analysis to identify candidate pathogenic genes of OS by using three Gene Expression Omnibus (GEO) databases (GSE66673, GSE49003 and GSE37552). GO and KEGG enrichment analysis were utilized to predict the functional annotation and potential pathways of differentially expressed genes...
Publication date: May 2019Source: European Journal of Cancer, Volume 113Author(s): Billal Tedbirt, Michel De Pontville, Pierre Branger, Camille Picard, Barouyr Baroudjian, Céleste Lebbé, Antoine F. Carpentier, Julie Delyon, PATIO group
Publication date: May 2019Source: European Journal of Cancer, Volume 113Author(s): Chia-Yu Chen, Chang-Fang Chiu, Li-Yuan Bai
Related ArticlesPretreatment financial toxicity predicts progression-free survival following concurrent chemoradiotherapy for locally advanced non-small-cell lung cancer. Future Oncol. 2019 Apr 12;: Authors: Klein J, Bodner W, Garg M, Kalnicki S, Ohri N Abstract AIM: Financial toxicity (FT) describes patients' burden from out-of-pocket medical treatment costs. We studied associations between patient-reported pretreatment FT, socioeconomic status and...
Related ArticlesA multicenter real-world study of bevacizumab in heavily pretreated malignant gliomas: clinical benefit is a plausible end point? Future Oncol. 2019 Apr 12;: Authors: Villani V, Fabi A, Tanzilli A, Pasqualetti F, Lombardi G, Vidiri A, Gonnelli A, Molinari A, Cantarella M, Bellu L, Terrenato I, Carosi M, Maschio M, Telera SM, Carapella CM, Cognetti F, Paiar F, Zagonel V, Pace A Abstract AIM: This multicenter, retrospective study evaluates...
Related ArticlesExhaled breath biopsy: a new cancer detection paradigm. Future Oncol. 2019 Apr 12;: Authors: Abderrahman B PMID: 30977676 [PubMed - as supplied by publisher]
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Related ArticlesAIPAC: a Phase IIb study of eftilagimod alpha (IMP321 or LAG-3Ig) added to weekly paclitaxel in patients with metastatic breast cancer. Future Oncol. 2019 Apr 12;: Authors: Dirix L, Triebel F Abstract Eftilagimod alpha (IMP321), a soluble dimeric recombinant form of LAG-3, is a first-in-class antigen presenting cell activator under clinical development. By stimulating dendritic cells through MHC class II molecules, IMP321 was proven to...
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Related ArticlesIMpassion132 Phase III trial: atezolizumab and chemotherapy in early relapsing metastatic triple-negative breast cancer. Future Oncol. 2019 Apr 12;: Authors: Cortés J, André F, Gonçalves A, Kümmel S, Martín M, Schmid P, Schuetz F, Swain SM, Easton V, Pollex E, Deurloo R, Dent R Abstract The PD-L1 inhibitor atezolizumab received US FDA accelerated approval as treatment for programmed death-ligand 1 (PD-L1)-positive metastatic triple-negative...
Related ArticlesThe hematologic parameters in metastatic castration-resistant prostate cancer patients treated with abiraterone acetate. Future Oncol. 2019 Apr 12;: Authors: Onal C, Sedef AM, Kose F, Oymak E, Guler OC, Sumbul AT, Aksoy S, Akkus Yildirim B, Besen AA, Muallaoglu S, Mertsoylu H, Ozyigit G Abstract Currently, there are no predictive markers of response to abiraterone. We calculated neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte...
Publication date: Available online 12 April 2019Source: Surgical Oncology Clinics of North AmericaAuthor(s): Luke D. Rothermel, Amod A. Sarnaik, Nikhil I. Khushalani, Vernon K. Sondak
Publication date: Available online 12 April 2019Source: Surgical Oncology Clinics of North AmericaAuthor(s): Mohammad S. Jafferji, James C. Yang
Publication date: Available online 12 April 2019Source: Surgical Oncology Clinics of North AmericaAuthor(s): Tyler W. Hulett, Bernard A. Fox, David J. Messenheimer, Sebastian Marwitz, Tarsem Moudgil, Michael E. Afentoulis, Keith W. Wegman, Carmen Ballesteros-Merino, Shawn M. Jensen
Cancers, Vol. 11, Pages 531: Efficacy of a Selective Binder of αVβ3 Integrin Linked to the Tyrosine Kinase Inhibitor Sunitinib in Ovarian Carcinoma Preclinical Models Cancers doi: 10.3390/cancers11040531 Authors: Andrea Sartori Cristina Corno Michelandrea De Cesare Eugenio Scanziani Lucia Minoli Lucia Battistini Franca Zanardi Paola Perego Ovarian carcinoma, the most lethal gynecological cancer, is characterized by late diagnosis, with drug resistance limiting the...
AbstractObjectivesPhysical activity is associated with better quality of life (QOL) among breast cancer survivors. However, it is unknown the extent to which time spent sedentary or replacing this time with active behaviors may affect QOL. Our aim was to determine the effect of substituting time between sedentary and active behaviors on QOL indicators in breast cancer survivors.MethodsAn isotemporal substitution approach was used to examine the associations of reallocating time to sedentary...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00306932607174,00302841026182,alsfakia@gmail.com
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