Related Articles Hemophagocytic relapsed intramedullary plasmacytoma. Int J Hematol. 2020 Jun;111(6):888-890 Authors: Mouhieddine TH, Barlogie B, Teruya-Feldstein J Abstract We report a case of a relapsed hemophagocytic intramedullary plasmacytoma, previously non-phagocytic, in conjunction with development of a new clone with different cytogenetic abnormalities forming a solitary plasmacytoma. PMID: 31900879 [PubMed - indexed for MEDLINE]
Related Articles Immunophenotypic analysis of cerebrospinal fluid reveals concurrent development of ATL in the CNS of a HAM/TSP patient. Int J Hematol. 2020 Jun;111(6):891-896 Authors: Takeda R, Ishigaki T, Ohno N, Yokoyama K, Kawamata T, Fukuyama T, Araya N, Yamano Y, Uchimaru K, Tojo A Abstract Both adult T-cell leukemia/lymphoma (ATL) and human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP)...
Related Articles Primary hyperparathyroidism presenting as a brown tumor in the mandible: a case report. BMC Endocr Disord. 2020 Jan 13;20(1):6 Authors: Xu B, Yu J, Lu Y, Han B Abstract BACKGROUND: Primary hyperparathyroidism is characterized by hypercalcemia and elevated or inappropriately normal serum levels of parathyroid hormone. Brown tumor of bone is a rare non-neoplastic lesion resulted from abnormal bone metabolism in hyperparathyroidism....
Related Articles Clinicopathological and Prognostic Characteristics of CD276 (B7-H3) Expression in Adrenocortical Carcinoma. Dis Markers. 2020;2020:5354825 Authors: Liang J, Liu Z, Pei T, Xiao Y, Zhou L, Tang Y, Zhou C, Wu K, Zhang F, Zhang F, Yin X, Chen N, Wei X, Lu Y, Zhu Y Abstract Background: Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumor with a high tumor recurrence rate and poor postoperative survival. Recent studies...
Related Articles How I treat malignant pleural mesothelioma. ESMO Open. 2020 03;4(Suppl 2): Authors: Viscardi G, Di Liello R, Morgillo F Abstract Malignant pleural mesothelioma is a rare and aggressive malignancy mostly associated with occupational asbestos exposure. Prognosis is poor and only highly selected patients may benefit from aggressive surgical management, also as part of a multimodal approach. In advanced disease, the combination...
Related Articles Multiple Cerebral Hemorrhages With Microbleeds in Intravascular Large B-Cell Lymphoma. J Stroke Cerebrovasc Dis. 2020 Jun;29(6):104798 Authors: Kimura M, Fujiwara S, Tanaka A, Omura Y, Yamashita D, Hinoda T, Sakai N, Kohara N Abstract This is an extremely rare reported case of intravascular large B-cell lymphoma (IVLBCL) presenting with acute hemorrhages and numerous microbleeds. An 80-year-old man presented with consciousness...
Related Articles Systemic amyloidosis: moving into the spotlight. Leukemia. 2020 05;34(5):1215-1228 Authors: Cohen OC, Wechalekar AD Abstract Systemic amyloidosis is a rare but increasingly recognised disease that is heterogeneous in presentation. Early diagnosis, whilst imperative, remains challenging but can improve prognosis and limit organ dysfunction. An increased repertoire of diagnostic imaging and histological techniques are becoming...
Related Articles Extraskeletal osteosarcoma associated with a benign hair follicle tumor in a dog. Can Vet J. 2020 05;61(5):525-529 Authors: Duckett ME, MacDonald-Dickinson V, Dickinson RM Abstract A rare presentation of an extraskeletal osteosarcoma, suspected to have evolved from chronic inflammation associated with a benign hair follicle tumor in a dog is described. The patient was treated with surgical excision, carboplatin, and toceranib....
Bronchial Fistula: Rare Complication of Treatment with Anlotinib. Zhongguo Fei Ai Za Zhi. 2020 Sep 29;: Authors: Deng P, Hu C, Li Y, Cao L, Yang H, Li M, An J, Jiang J, Gu Q Abstract BACKGROUND: Anlotinib is a newly developed small molecule multiple receptor tyrosine kinase (RTK) inhibitor that was approved for the treatment of patients with lung cancer in China. We aim to report 3 cases of rare complication of anlotinib-bronchial fistula (BF)...
Prognostic Factors in Childhood Anaplastic Large Cell Lymphoma: Long Term Results of the International ALCL99 Trial. Cancers (Basel). 2020 Sep 24;12(10): Authors: Mussolin L, Le Deley MC, Carraro E, Damm-Welk C, Attarbaschi A, Williams D, Burke A, Horibe K, Nakazawa A, Wrobel G, Mann G, Csóka M, Uyttebroeck A, Fernández-Delgado Cerdá RF, Beishuizen A, Mellgren K, Burkhardt B, Klapper W, Turner SD, D'Amore ESG, Lamant L, Reiter A, Woessmann W, Brugières L, Pillon...
Targeting Liver Cancer Stem Cells: An Alternative Therapeutic Approach for Liver Cancer. Cancers (Basel). 2020 Sep 24;12(10): Authors: Lee HY, Hong IS Abstract The first report of cancer stem cell (CSC) from Bruce et al. has demonstrated the relatively rare population of stem-like cells in acute myeloid leukemia (AML). The discovery of leukemic CSCs prompted further identification of CSCs in multiple types of solid tumor. Recently, extensive...
Beyond Traditional Morphological Characterization of Lung Neuroendocrine Neoplasms: In Silico Study of Next-Generation Sequencing Mutations Analysis across the Four World Health Organization Defined Groups. Cancers (Basel). 2020 Sep 24;12(10): Authors: Centonze G, Biganzoli D, Prinzi N, Pusceddu S, Mangogna A, Tamborini E, Perrone F, Busico A, Lagano V, Cattaneo L, Sozzi G, Roz L, Biganzoli E, Milione M Abstract Lung neuroendocrine neoplasms...
[Clinical characteristics of primary aldosteronism with concurrent adrenal Cushing's syndrome]. Zhonghua Yi Xue Za Zhi. 2020 Sep 29;100(36):2828-2833 Authors: Guo JC, Chen XY, Zhang JQ, Guo XH Abstract Objective: To analyze and summarize the clinical characteristics of primary aldosteronism (PA) with concurrent adrenal Cushing's syndrome (ACS). Methods: The clinical, imaging and pathological data of 87 patients with PA admitted to Peking University...
Benefits of molecular profiling with next-generation sequencing for the diagnosis and prognosis of myeloproliferative neoplasms in splanchnic vein thrombosis. J Hepatol. 2020 Sep 25;: Authors: Kiladjian JJ, Debureaux PE, Plessier A, Soret-Dulphy J, Valla D, Cassinat B, Rautou PE PMID: 32988658 [PubMed - as supplied by publisher]
Prognostic Factors in Patients Undergoing Pulmonary Resection for Sarcomatoid Carcinomas of the Lung. Balkan Med J. 2020 Sep 29;: Authors: Özkan B, Erdoğdu E, Duman S, Amirov F, Çimenoğlu B, Özlük Y, Kara M, Yılmazbayhan D, Toker A Abstract INTRODUCTION: Pulmonary sarcomatoid carcinomas are very rare lung neoplasms, and no consensus exists regarding the optimal treatment. The prognosis of sarcomatoid carcinomas has been reported to be unfavorable...
Morphology of tumor and nontumor tissue in liver resection specimens for hepatocellular carcinoma following nivolumab therapy. Mod Pathol. 2020 Sep 28;: Authors: Simoes CC, Thung SN, Fiel MI, Sung MW, Schwartz ME, Ward SC Abstract Nivolumab is an immune checkpoint inhibitor (ICI) approved for treatment of many cancers, including hepatocellular carcinoma (HCC). Liver injury is a known complication in patients treated with nivolumab for nonliver...
Ovarian pulmonary-type small cell carcinoma diagnosed by means of ascitic fluid cytology: A case report with immunocytochemical analysis. Cytopathology. 2020 Sep 28;: Authors: Ishikawa A, Fujisawa H, Yasumura N, Kuraoka K, Zaitsu J, Saito A, Kan A, Iwahiro K, Kimura F, Nakamura H, Mizunoe T, Taniyama K Abstract Primary ovarian small cell carcinomas are exceedingly rare neoplasms that account for less than 1% of ovarian carcinomas.1 Primary...
Distinctive phenotypes in two children with novel germline RUNX1 mutations - one with myeloid malignancy and increased fetal hemoglobin. Pediatr Hematol Oncol. 2020 Sep 29;:1-15 Authors: Bagla S, Regling KA, Wakeling EN, Gadgeel M, Buck S, Zaidi AU, Flore LA, Chicka M, Schiffer CA, Chitlur MB, Ravindranath Y Abstract RUNX1 associated familial platelet disorder (FPD) is a rare autosomal dominant hematologic disorder characterized by thrombocytopenia...
Hepatic resection for recurrent hepatocellular carcinoma during pregnancy: a case report. Surg Case Rep. 2020 Sep 29;6(1):229 Authors: Maeda T, Imai D, Wang H, Yugawa K, Kinjo N, Kawata K, Ikeda S, Edahiro K, Takeishi K, Iguchi T, Kayashima H, Harada N, Ninomiya M, Yamaguchi S, Konishi K, Tsutsui S, Matsuda H Abstract BACKGROUND: Hepatocellular carcinoma (HCC) during pregnancy is extremely rare. Treatment strategies for cancers detected during...
The Masquerading, Masculinizing Tumor: A Case Report and Review of the Literature. J Womens Health (Larchmt). 2020 Sep 29;: Authors: LeVee A, Suppogu N, Walsh C, Sacks W, Simon J, Shufelt C Abstract Androgen-producing tumors in women are rare neoplasms that can cause secondary virilizing characteristics. Of patients presenting with symptoms of hyperandrogenism, these tumors are found in ∼0.2% of cases. Androgen-producing tumors can arise from...
FUS-NFATC2 or EWSR1-NFATC2 Fusions Are Present in a Large Proportion of Simple Bone Cysts. Am J Surg Pathol. 2020 Sep 25;: Authors: Pižem J, Šekoranja D, Zupan A, Boštjančič E, Matjašič A, Mavčič B, Contreras JA, Gazič B, Martinčič D, Snoj Ž, Limpel Novak KA, Salapura V Abstract A simple bone cyst (SBC) is a benign bone lesion of unknown etiology. It can be differentiated from an aneurysmal bone cyst (ABC) by radiologic and histopathologic...
Acquired hemophagocytic lymphohistiocytosis as initial manifestation of multiple myeloma: A case report and literature review. Medicine (Baltimore). 2020 Sep 25;99(39):e22299 Authors: Mendes FR, Sobral KM, Culler HF, Couto SCF, Pereira J, Rocha V, Martinez GA, Lage LAPC Abstract INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is a condition characterized by a hyperinflammatory state and persistent macrophage activation, resulting in...
Related Articles Large-scale analyses identify a cluster of novel long noncoding RNAs as potential competitive endogenous RNAs in progression of hepatocellular carcinoma. Aging (Albany NY). 2019 11 23;11(22):10422-10453 Authors: Song M, Zhong A, Yang J, He J, Cheng S, Zeng J, Huang Y, Pan Q, Zhao J, Zhou Z, Zhu Q, Tang Y, Chen H, Yang C, Liu Y, Mo X, Weng D, Xia JC Abstract The abnormal expression of noncoding RNAs has attracted increasing...
Related Articles MRI Patterns of Extrapontine Lesion Extension in Diffuse Intrinsic Pontine Gliomas. AJNR Am J Neuroradiol. 2020 02;41(2):323-330 Authors: Makepeace L, Scoggins M, Mitrea B, Li Y, Edwards A, Tinkle CL, Hwang S, Gajjar A, Patay Z Abstract BACKGROUND AND PURPOSE: Diffuse intrinsic pontine glioma is a devastating childhood cancer that despite being primarily diagnosed by MR imaging alone, lacks robust prognostic imaging features....
Prognostic Factors in Childhood Anaplastic Large Cell Lymphoma: Long Term Results of the International ALCL99 Trial. Cancers (Basel). 2020 Sep 24;12(10): Authors: Mussolin L, Le Deley MC, Carraro E, Damm-Welk C, Attarbaschi A, Williams D, Burke A, Horibe K, Nakazawa A, Wrobel G, Mann G, Csóka M, Uyttebroeck A, Fernández-Delgado Cerdá RF, Beishuizen A, Mellgren K, Burkhardt B, Klapper W, Turner SD, D'Amore ESG, Lamant L, Reiter A, Woessmann W, Brugières L, Pillon...
[Research progress of immune checkpoint inhibitors in clinical diagnosis and treatment of non-small cell lung cancer]. Zhonghua Zhong Liu Za Zhi. 2020 Sep 23;42(9):713-717 Authors: Huang Y, Xu K, Wang W, Cui F, Zeng Y, Hao ZX, Cai WP, He JX, Liu J Abstract Lung cancer is currently the malignant tumor with the highest morbidity and mortality in the world, and the main type is non-small cell lung cancer. Immune checkpoint inhibitor is a landmark...
Liquid biopsy for ALK-positive early non-small-cell lung cancer predicts disease relapse. Future Oncol. 2020 Sep 29;: Authors: Li J, Dong W, Liu LN, Huang YJ, Xiao MF Abstract Background: We aimed to determine whether circulating tumor cells (CTCs) and cell-free DNA (cfDNA) aids in prognosis of relapse-free survival (RFS). Methods: Non-small cell lung cancer patients with ALK mutations were recruited prospectively. CTCs and cfDNA were quantified...
Nodal recurrences after stereotactic body radiotherapy for early stage non-small-cell lung cancer. Curr Probl Cancer. 2020 Sep 22;:100653 Authors: Tibdewal A, Pathak RS, Agarwal JP, Hoskote S, Mummudi N, Iyer V, Nair AG Abstract Lobectomy is considered the standard of care for early stage non-small-cell lung cancer. However, for those patients who remain unfit to undergo surgery due to advanced age, poor performance status, comorbidities, poor...
New Uses for Thromboelastography and Other Forms of Viscoelastic Monitoring in the Emergency Department: A Narrative Review. Ann Emerg Med. 2020 Sep 25;: Authors: Tyler PD, Yang LM, Snider SB, Lerner AB, Aird WC, Shapiro NI Abstract Patients frequently visit the emergency department with conditions that place them at risk of worse outcomes when accompanied by coagulopathy. Routine tests of coagulation-prothrombin time, partial thromboplastin...
Impact of obesity on voriconazole pharmacokinetics among pediatric hematopoietic cell transplant recipients. Antimicrob Agents Chemother. 2020 Sep 28;: Authors: Takahashi T, Smith AR, Jacobson PA, Fisher J, Rubin NT, Kirstein MN Abstract BACKGROUND: Voriconazole (VCZ) is an antifungal agent with wide inter- and intra- patient pharmacokinetic (PK) variability and narrow therapeutic index. Although obesity was associated with higher VCZ trough...
First Reported Case of Localized Extra-pulmonary Small Cell Carcinoma (EPSC) of the Esophagus Treated With Triple Therapy. Anticancer Res. 2020 Oct;40(10):5919-5923 Authors: Haag A, Jayakrishnan T, Shah D, Sandhu A, Monga D Abstract BACKGROUND/AIM: Early stage extra-pulmonary small cell carcinoma (EPSC) of the esophagus is very rare and is usually treated with chemo-radiation or surgical resection. CASE REPORT: A case of early stage...
In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine. Cancer Chemother Pharmacol. 2020 Sep 28;: Authors: Joshi A, Kiesel BF, Chaphekar N, Jones R, Guo J, Kunos CA, Taylor S, Chu E, Venkataramanan R, Beumer JH Abstract PURPOSE: To investigate the metabolic pathways of triapine in primary cultures of human hepatocytes and human hepatic subcellular fractions; to investigate interactions of triapine with tenofovir...
Treatment of rheumatic immune-related adverse events due to cancer immunotherapy with immune checkpoint inhibitors-is it time for a paradigm shift? Clin Rheumatol. 2020 Sep 28;: Authors: Chatzidionysiou K, Liapi M, Tsakonas G, Gunnarsson I, Catrina A Abstract Immunotherapy has revolutionized cancer treatment during the last years. Several monoclonal antibodies that are specific for regulatory checkpoint molecules, that is, immune checkpoint...
Fear of cancer recurrence among young adult cancer survivors-exploring long-term contributing factors in a large, population-based cohort. J Cancer Surviv. 2020 Sep 28;: Authors: Vandraas KF, Reinertsen KV, Kiserud CE, Lie HC Abstract PURPOSE: Fear of cancer recurrence (FCR) may be debilitating, yet knowledge of FCR among the growing population of long-term young adult cancer survivors (YACS) is scarce. We explored risk of FCR and associated...
Could pre-filled safety syringes facilitate the adoption of home administration for cancer patients?
Could pre-filled safety syringes facilitate the adoption of home administration for cancer patients? J Oncol Pharm Pract. 2020 Sep 29;:1078155220961463 Authors: I'ons G Abstract Today, healthcare systems around the world are under increasing pressure, not least with the current health crisis. One of the leading efforts to relieve this burden in recent years has been through the promotion and facilitation of self-administration, particularly...
Cost-effectiveness of Lutetium [177Lu] oxodotreotide versus best supportive care with octreotide in patients with midgut neuroendocrine tumors in France. J Med Econ. 2020 Sep 29;:1 Authors: Leeuwenkamp O, Smith-Palmer J, Ortiz R, Werner A, Valentine W, Blachier M, Walter T Abstract Background and Aims: In France, there are approximately 2,400 new cases of neuroendocrine tumors (NETs) annually. Peptide receptor radionuclide therapy with 177Lu-Dotatate...
[Masterplan 2025 of the Austrian Society of Pneumology (ASP)-the expected burden and management of respiratory diseases in Austria]. Wien Klin Wochenschr. 2020 Sep;132(Suppl 3):89-113 Authors: Studnicka M, Baumgartner B, Bolitschek J, Doberer D, Eber E, Eckmayr J, Hartl S, Hesse P, Jaksch P, Kink E, Kneussl M, Lamprecht B, Olschewski H, Pfleger A, Pohl W, Prior C, Puelacher C, Renner A, Steflitsch W, Stelzmüller I, Täubl H, Vonbank K, Wagner M, Wantke F, Wass...
Initial Steps Towards a Clinical FLASH Radiotherapy System: Pediatric Whole Brain Irradiation with 40 MeV Electrons at FLASH Dose Rates. Radiat Res. 2020 Sep 29;: Authors: Breitkreutz DY, Shumail M, Bush KK, Tantawi SG, Maxim PG, Loo BW Abstract In this work, we investigated the delivery of a clinically acceptable pediatric whole brain radiotherapy plan at FLASH dose rates using two lateral opposing 40-MeV electron beams produced by a practically...
407 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/09/30PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Spontaneous diaphragmatic rupture following neoadjuvant chemotherapy and cytoreductive surgery in malignant pleural mesothelioma: A case report and review of the literature. Int J Surg Case Rep. 2020 Sep 16;: Authors: Cattaneo M, Mendogni P, Damarco F, Tosi D Abstract INTRODUCTION: Diaphragmatic rupture (DR) is an acquired diaphragmatic defect that can cause herniation of abdominal organs into the chest. It is usually a trauma-related lesion,...
Glomus tumor-induced lower extremity pain: A case report. Int J Surg Case Rep. 2020 Sep 17;75:352-356 Authors: Kloping LP, Widhiyanto L, Irianto KA, Sindrawati O, Kloping YP Abstract INTRODUCTION: Glomus tumor located in the lower limb could be easily mistaken as lower extremity pain whether it is radiating, sciatic, or just a localized one. This could lead to misdiagnosis and improper management. PRESENTATION OF CASE: This case reported...
Inguinal lymph node metastasis of bladder carcinoma after radical cystectomy: A case report and review of literature. Int J Surg Case Rep. 2020 Sep 21;75:385-389 Authors: Moussa M, Chakra MA, Papatsoris A, Dellis A, Saad W, Chahine NB Abstract INTRODUCTION: Lymph node metastasis in bladder cancer (BC) is common and has been associated with a very poor prognosis. Bc rarely metastasizes to inguinal lymph nodes. PRESENTATION OF CASE:...
Synovial cyst of the acromioclavicular joint with and without rotator cuff tear: A case series of two patients. Int J Surg Case Rep. 2020 Sep 16;75:390-393 Authors: De Maio F, Di Marcantonio A, De Luna V, Caterini A, Tresoldi I, Farsetti P Abstract INTRODUCTION: Acromioclavicular joint cyst (AJC) is a very uncommon condition of the shoulder observed in elderly patients, caused by a degenerative acromioclavicular (AC) joint, frequently associated...
The management of acute lower gastrointestinal bleeding using a Sengstaken-Blakemore tube. Int J Surg Case Rep. 2020 Sep 21;75:394-397 Authors: Fadel MG, Boshier PR, Howell AM, Iskandarani M, Tekkis P, Kontovounisios C Abstract INTRODUCTION: Acute lower gastrointestinal haemorrhage can potentially be life-threatening. We present a case of a massive rectal bleed which was managed successfully with a balloon tamponade device designed for upper...
Nodular lesion on the posterior dorsal surface of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 27;: Authors: Silva EV, Lança MLA, Silveira HA, Bufalino A, Navarro CM, Ribeiro-Silva A, León JE, Yamamoto de Almeida L PMID: 32988806 [PubMed - as supplied by publisher]
Regulatory T-cell expansion in oral and maxillofacial Langerhans cell histiocytosis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 08;: Authors: Zhang C, Gao J, He J, Liu C, Lv X, Yin X, Deng Y, Lu Z, Tian Z Abstract OBJECTIVE: Langerhans cell histiocytosis (LCH) is a rare myeloid-origin neoplasm characterized by the expansion and dissemination of CD1 a+/CD207+ dendritic cells (LCH cells), but the rarity of its occurrence has long impeded...
Oxidative-protective effect of nuclear receptor coactivator 7 on arecoline-induced endothelial-to-mesenchymal transition. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 21;: Authors: Wang Y, Luo D, Yuan X, Luo Y, Cheng X, Gao Y, Xie X Abstract OBJECTIVE: Overproduction of reactive oxygen species (ROS) has been implicated in inflammatory activities and tumorigenesis in oral submucous fibrosis (OSF). Nuclear receptor coactivator 7 (NCOA7)...
Central odontogenic fibroma: an international multicentric study of 62 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 27;: Authors: Roza ALOC, Sousa EM, Leite AA, Amaral-Silva GK, Morais TML, Wagner VP, Schuch LF, Vasconcelos ACU, de Arruda JAA, Mesquita RA, Fonseca FP, Abrahão AC, Agostini M, de Andrade BAB, da Silveira EJD, Martínez-Flores R, Rondanelli BM, Alberdi-Navarro J, Robinson L, Marin C, Assunção Júnior JNR, Valiati R, Fregnani ER, Santos-Silva...
An Invited Commentary on "distal pancreatectomy with multiviseral resection: A retrospective multicenter study - Case series" (International Journal of surgery 2020 Epub ahead of print). Int J Surg. 2020 Sep 26;: Authors: Chiarello MM, Brisinda G PMID: 32992026 [PubMed - as supplied by publisher]
CORRIGENDUM TO: TOWARD NATIONAL CT DIAGNOSTIC REFERENCE LEVELS IN THE UNITED ARAB EMIRATES: A MULTICENTER REVIEW OF CT DOSE INDEX AND DOSE LENGTH PRODUCT. Radiat Prot Dosimetry. 2020 Sep 29;: Authors: Abuzaid MM, Elshami W, El Serafi A, Hussien T, McConnell JR, Tekin HO PMID: 32990317 [PubMed - as supplied by publisher]
Evaluation of Specific Absorption Rate in the Far-Field, Near-to-Far Field and Near-Field Regions for Integrative Radiofrequency Exposure Assessment. Radiat Prot Dosimetry. 2020 Sep 28;: Authors: Liorni I, Capstick M, van Wel L, Wiart J, Joseph W, Cardis E, Guxens M, Vermeulen R, Thielens A Abstract The specific absorption rate (SAR) induced by wireless radiofrequency (RF) systems depends on different parameters. Previously, SAR was mainly...
Nicorandil and Atorvastatin Attenuate Carbon Tetrachloride - Induced Liver Fibrosis in Rats. Immunopharmacol Immunotoxicol. 2020 Sep 28;:1-29 Authors: Abdel-Sattar AR, Abo-Saif AA, Aboyoussef AM Abstract The present study aimed to evaluate the possible hepatoprotective effects of nicorandil and atorvastatin against experimentally induced liver fibrosis.Wistar male rats wereassigned tofivegroups;control group, fibrosis group, the remaining three...
Clinical efficacy of γ-globulin combined with dexamethasone and methylprednisolone, respectively, in the treatment of acute transverse myelitis and its effects on immune function and quality of life. Exp Ther Med. 2020 Nov;20(5):104 Authors: Wang P, Zhang S, Lv H, Qiao G, Zhong X, Li H, Zhang L Abstract Effects of γ-globulin combined with dexamethasone or methylprednisolone in the treatment of acute transverse myelitis (ATM) were investigated....
Serum miRNA-142 and BMP-2 are markers of recovery following hip replacement surgery for femoral neck fracture. Exp Ther Med. 2020 Nov;20(5):105 Authors: Gao H, Wang X Abstract The present study aimed to investigate the changes in miRNA-142 and bone morphogenetic protein-2 (BMP-2) expression before and after hip replacement surgery, and to determine their association with receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG)....
Melatonin prevents the binding of vascular endothelial growth factor to its receptor and promotes the expression of extracellular matrix-associated genes in nucleus pulposus cells. Exp Ther Med. 2020 Nov;20(5):106 Authors: Shen C, Li Y, Chen Y, Huang L, Zhang F, Wu W Abstract The mechanisms of intervertebral disc degeneration (IDD) involve numerous factors, including loss of the extracellular matrix (ECM) and vascular ingrowth. Melatonin has...
Evaluation of immune-biomarker expression in high-grade soft-tissue sarcoma: HLA-DQA1 expression as a prognostic marker. Exp Ther Med. 2020 Nov;20(5):107 Authors: Bae JY, Choi KU, Kim A, Lee SJ, Kim K, Kim JY, Lee IS, Chung SH, Kim JI Abstract High-grade soft-tissue sarcoma (STS) is a highly malignant neoplasm with a poor overall prognosis. Numerous prognostic factors determine tumor progression and patient outcomes. Various immune-associated...
Effect of simultaneous surgical treatment in scoliosis associated with intraspinal abnormalities: A retrospective study. Exp Ther Med. 2020 Nov;20(5):108 Authors: Wang K, Shang F, Jian FZ, Wu H Abstract To evaluate the outcomes of single-stage surgical treatment for spinal deformity and coexisting intraspinal pathologies, 12 patients who underwent single-stage surgical treatment for spinal deformity and co-existing intraspinal abnormalities...
Lithium chloride ameliorated spatial cognitive impairment through activating mTOR phosphorylation and inhibiting excessive autophagy in the repeated cerebral ischemia-reperfusion mouse model. Exp Ther Med. 2020 Nov;20(5):109 Authors: Xiao Y, Fan M, Jin W, Li WA, Jia Y, Dong Y, Jiang X, Xu J, Meng N, Lv P Abstract Lithium has been previously demonstrated to alleviate cognitive impairment caused by neurodegenerative diseases and acute brain injuries;...
SNHG1 promotes proliferation, migration and invasion of bladder cancer cells via the PI3K/AKT signaling pathway. Exp Ther Med. 2020 Nov;20(5):110 Authors: Du Q, Chen J Abstract Long non-coding RNA (lncRNA) small nucleolar RNA host gene 1 (SNHG1) has been previously reported to mediate a number of functions during the progression of cancer. However, its involvement in bladder cancer remain unclear. The aim of the present study was to investigate...
Pretreatment with human urine-derived stem cells protects neurological function in rats following cardiopulmonary resuscitation after cardiac arrest. Exp Ther Med. 2020 Nov;20(5):112 Authors: Pan C, Zheng X, Wang L, Chen Q, Lin Q Abstract Cardiopulmonary resuscitation (CPR) after cardiac arrest (CA) often leads to neurological deficits in the absence of effective treatment. The aim of the present basic research study was to investigate the...
Tac2-N serves an oncogenic role and promotes drug resistance in human gastric cancer cells. Exp Ther Med. 2020 Nov;20(5):113 Authors: Shen L, Zhang P, Wang J, Ji P Abstract Gastric cancer is one of the most common types of malignancy worldwide. Tac2-N (TC2N) has been reported to serve as either an oncogene or tumor suppressor in numerous different types of cancer; however, the role of TC2N in gastric cancer remains poorly understood. The present...
Effect of endometrioma and its surgical excision on fertility (Review). Exp Ther Med. 2020 Nov;20(5):114 Authors: Jiang D, Nie X Abstract Endometrioma is the cystic lesion of ovaries originating from endometrial glands and stroma; it is identified in 17-44% of patients with endometriosis. Numerous existing studies have reported the association between endometrioma and infertility. However, an absolute cause-effect association requires further...
Impact of COVID-19 pandemic on microsurgery fellowships. J Plast Reconstr Aesthet Surg. 2020 Sep 20;: Authors: Lymperopoulos NS, Dunne J, Morgan M, Mackey S, Roblin P, Ramsey K, Nanidis T PMID: 32988775 [PubMed - as supplied by publisher]
Data analysis of recent cleft lip and palate surgery in Korea using the National Health Insurance Service (NHIS) database. J Plast Reconstr Aesthet Surg. 2020 Sep 08;: Authors: Mo YW, Lee DL Abstract BACKGROUND: No national epidemiological investigations have been conducted on several aspects of cleft lip and palate surgery. METHODS: The study was performed using the data of 5727 people who underwent cleft lip and palate surgery during...
[Hot flushes and breast cancer with positive hormone receptors: Mechanisms and management]. Bull Cancer. 2020 Sep 25;: Authors: Cavadias I, Rouzier R, Lerebours F, Héquet D Abstract Breast cancer is the most frequently diagnosed cancer in women and the first cause of cancer death in France. Among the different subtypes of breast cancer, the predominant form is characterized by positive hormone receptors (more than 70% of breast cancers). Hormone...
Rodent models for cerebral infarction are useful for studying human focal ischemic cerebral infarction, by simulating etiological and pathophysiological mechanisms. However, differences in the selection of anesthetic drugs, surgical methods and other factors may affect the extent to which preclinical models reflect the human condition. This review summarizes these factors. We searched pertinent literature from the MEDLINE and Web of Science databases, and reviewed differences in rodent strain, anesthesia...
Mindfulness meditation has become a promising intervention for promoting health and well-being. Neuroimaging studies have shown its beneficial effects on brain functional activity, connectivity, and structures following months to years of practice. A series of randomized controlled trials indicated that one form of mindfulness meditation, the integrative body-mind training (IBMT) induces brain functional and structural changes in brain regions related to self-control networks such as the anterior...
Closed-head, frontal impacts in which the brain undergoes both lateral and rotational acceleration comprise the majority of human traumatic brain injury (TBI). Here, we utilize a clinically relevant model to examine the effects of a single concussion on aspects of brain integrity: the blood–brain barrier, the perineuronal nets (PNNs), and diffuse axonal injury. Adult, male Sprague–Dawley rats received either a frontal, closed-head concussive TBI, or no injury and were evaluated at 1- or 7-day post-injury....
Previous studies have shown that the cross-modal pre-preparation effect is an important factor for audiovisual integration. However, the facilitating influence of the pre-preparation effect on the integration of emotional cues remains unclear. Therefore, this study examined the emotional pre-preparation effect during the multistage process of audiovisual integration. Event-related potentials (ERPs) were recorded while participants performed a synchronous or asynchronous integration task with fearful...
The small molecule inhibitor PR-619 protects retinal ganglion cells against glutamate excitotoxicity
Glutamate excitotoxicity may contribute to the death of retinal ganglion cell (RGC) in glaucoma and other retinal diseases such as ischemia. Deubiquitinating enzyme (DUB) inhibitors are emerging as attractive targets for pharmacological intervention in neurodegenerative diseases. However, the role of PR-619, the broad spectrum DUB inhibitor, on RGCs under different stressful environment remains largely unknown. This study was designed to investigate the role of PR-619 in regulating mitophagy of RGCs...
Objective The neuro-anatomical substrates of major depressive disorder (MDD) remain poorly understood. Brain-derived neurotrophic factor (BDNF) gene polymorphism (Val66Met /rs6265) is associated with neuro-plasticity and development. In the present study, we explore the influence of BDNF gene polymorphism on cortical thickness in nonelderly, first episode, drug-naive patients with MDD. Methods Two hundred and sixteen participants (105 MDD patients and 111 healthy controls) were divided...
A clinical profile of revision cochlear implant surgery: MERF experience. Cochlear Implants Int. 2020 Sep 29;:1-7 Authors: Rayamajhi P, Kurkure R, Castellino A, Kumar S, Ha M, Nandhan R, Kameswaran M Abstract Objective: To study the prevalence of revision cochlear implant study in a tertiary care referral center. To assess the various indications and surgical outcomes of revision cochlear implant surgery. Methods: A retrospective chart review...
Related Articles EEG lateralization and seizure outcome following peri-insular hemispherotomy for pediatric hemispheric epilepsy. Childs Nerv Syst. 2019 07;35(7):1189-1195 Authors: Abraham AP, Thomas MM, Mathew V, Muthusamy K, Yoganathan S, Jonathan GE, Prabhu K, Daniel RT, Chacko AG Abstract OBJECTIVE: To determine whether preoperative non-lateralizing scalp electroencephalography (EEG) influences seizure outcome following peri-insular hemispherotomy...
Related Articles A child with a stroke, drug-refractory epilepsy and congenital heart disease: can a hemispherectomy be safely performed between staged cardiac procedures? Childs Nerv Syst. 2019 07;35(7):1245-1249 Authors: Jain P, Haller C, Pulcine E, Ochi A, Dipchand A, Weiss SK, Chin V, Ibrahim GM Abstract BACKGROUND: The safety of hemispherectomy between staged cardiac procedures is unknown and not previously reported. METHOD: Retrospective...
Related Articles A systematic review of the association between coping strategies and quality of life among caregivers of children with chronic illness and/or disability. BMC Pediatr. 2019 07 01;19(1):215 Authors: Fairfax A, Brehaut J, Colman I, Sikora L, Kazakova A, Chakraborty P, Potter BK, Canadian Inherited Metabolic Diseases Research Network Abstract BACKGROUND: Parents of children with chronic illness have reported decreased psychological...
Related Articles Reachability Analysis of Neural Masses and Seizure Control Based on Combination Convolutional Neural Network. Int J Neural Syst. 2020 Jan;30(1):1950023 Authors: Ma Z Abstract Epileptic seizures arise from synchronous firing of multiple spatially separated neural masses; therefore, many synchrony measures are used for seizure detection and characterization. However, synchrony measures reflect only the overall interaction strength...
Related Articles The effects of antihistamine on the duration of the febrile seizure: A single center study with a systematic review and meta-analysis. Brain Dev. 2020 Feb;42(2):103-112 Authors: Sugitate R, Okubo Y, Nariai H, Matsui A Abstract BACKGROUND: Several studies have investigated the potential effects of antihistamines on febrile seizure. However, these findings are inconsistent across the studies. METHOD: A retrospective...
Related Articles Mental and somatic comorbidity of depression: a comprehensive cross-sectional analysis of 202 diagnosis groups using German nationwide ambulatory claims data. BMC Psychiatry. 2020 03 30;20(1):142 Authors: Steffen A, Nübel J, Jacobi F, Bätzing J, Holstiege J Abstract BACKGROUND: Depression is frequently accompanied by other mental disorders and various somatic diseases; however, previous comorbidity studies often relied on...
Families' Perception of Classic Ketogenic Diet Management in Acute Medical Conditions: A Web-Based Survey. Nutrients. 2020 Sep 24;12(10): Authors: Pasca L, Varesio C, Ferraris C, Guglielmetti M, Trentani C, Tagliabue A, Veggiotti P, De Giorgis V Abstract Objective: To describe families' experiences in managing epileptic patients undergoing ketogenic dietary therapies (KDTs) in acute medical settings. Methods: We conducted a short online survey...
Perception of service users and their caregivers on primary care-based mental health services: a qualitative study in Nepal. BMC Fam Pract. 2020 Sep 28;21(1):202 Authors: Luitel NP, Jordans MJD, Subba P, Komproe IH Abstract BACKGROUND: Integration of mental health services into primary health care systems has been advocated as a strategy to minimize the tremendous mental health treatment gap, particularly in low- and middle-income countries....
Severe pallid breath-holding spells treated with low-dose theophylline. Brain Dev. 2020 Sep 25;: Authors: Sato A, Oda Y, Asakai H Abstract BACKGROUND: The medical treatment for severe pallid breath-holding spells accompanied with severe bradycardia or transient cardiac arrest is controversial. Although various medications have been reported to be effective, patients treated with pacemaker insertion are not always evaluated for pharmacological...
An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy. Nat Biomed Eng. 2020 Sep 28;: Authors: Wang C, Sun W, Zhang J, Zhang J, Guo Q, Zhou X, Fan D, Liu H, Qi M, Gao X, Xu H, Gao Z, Tian M, Zhang H, Wang J, Wei Z, Long NJ, Mao Y, Li C Abstract For patients with drug-resistant focal epilepsy, excision of the epileptogenic zone is the most effective treatment...
PHARMACOLOGICAL TREATMENT OF FOCAL EPILEPSY IN ADULTS: AN EVIDENCE BASED APPROACH. Expert Opin Pharmacother. 2020 Sep 29;: Authors: Mula M Abstract INTRODUCTION: Focal seizures represent the most common seizure type and focal epilepsies the most common epilepsy type. Anti-seizure medications (ASMs) still represent the main form of treatment for epilepsy. AREAS COVERED: The aim of this review article is to provide an overview of available...
[Cenobamate-a new perspective for epilepsy treatment]. Nervenarzt. 2020 Sep 29;: Authors: Steinhoff BJ Abstract In spite of the introduction of numerous new antiseizure drugs (ASD) over the last decades, the percentage of drug-resistant epilepsies has remained almost stable. To achieve seizure freedom in such patients with any modified ASD regimen is an exception. Cenobamate (CNB) is a new ASD that showed unusually high efficacy in the pivotal...
Neuroprotective role of chrysin-loaded poly(lactic-co-glycolic acid) nanoparticle against kindling-induced epilepsy through Nrf2/ARE/HO-1 pathway. J Biochem Mol Toxicol. 2020 Sep 29;:e22634 Authors: Zhang Y, Zhao J, Afzal O, Kazmi I, Al-Abbasi FA, Altamimi ASA, Yang Z Abstract Chrysin is the major bioactive compound of blue passionflower, an important medicinal plant used in traditional herbal formulations since ancient times. In the present...
White matter and neurite morphology differ in psychogenic nonepileptic seizures. Ann Clin Transl Neurol. 2020 Sep 29;: Authors: Goodman AM, Allendorfer JB, Blum AS, Bolding MS, Correia S, Ver Hoef LW, Gaston TE, Grayson LE, Kraguljac NV, Lahti AC, Martin AN, Monroe WS, Philip NS, Tocco K, Vogel V, LaFrance WC, Szaflarski JP Abstract OBJECTIVE: To further evaluate the relationship between the clinical profiles and limbic and motor brain regions...
Publication date: Available online 29 September 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Jia Xu, Zin Mar Aung, Sousan Cheong, Taeho Won, Ruhong Zhang, Feng Xu, Jiajun Fan, Dong Han
Prognostic value of immune related genes in lung adenocarcinoma. Oncol Lett. 2020 Nov;20(5):259 Authors: Wang H, Wang MS, Wang Y, Huang YQ, Shi JP, Ding ZL, Wang WJ Abstract Lung cancer has the highest incidence and mortality rates of all cancers in China. Immune-related genes and immune infiltrating lymphocytes are involved in tumor growth, and in the past decade, immunotherapy has become increasingly important in the treatment of lung cancer....
miR-4295 promotes cell proliferation, migration and invasion of osteosarcoma through targeting interferon regulatory factor 1. Oncol Lett. 2020 Nov;20(5):260 Authors: Cheng JP, Huang B, Duan JH, Yi KJ, Zhuang ZL Abstract Osteosarcoma (OS) is the most common form of primary malignant bone tumor. Despite encouraging progress in the treatment of OS, the survival rate for patients with OS has remained unchanged over the past 40 years. It has been...
Steroid 5 alpha-reductase 2 enzyme variants, biomass exposure and tobacco use in Mexican patients with prostate cancer. Oncol Lett. 2020 Nov;20(5):261 Authors: Delgado-Balderas JR, Gallardo-Blanco HL, Yee-De León JF, Rivas-Estilla AM, Soto-García B, Aráiz-Hernández D, Garza-Guajardo R, Náñez-Marín M, Hernández-Barajas D, García-Bailón AM, Vízcarra-Mata G, Ocaña-Munguía MA, Gómez-Guerra LS, Sánchez-Domínguez CN Abstract The presence of the genetic...
LINC00294 induced by GRP78 promotes cervical cancer development by promoting cell cycle transition. Oncol Lett. 2020 Nov;20(5):262 Authors: Qiu J, Zhou S, Cheng W, Luo C Abstract Cervical cancer is one of the most common gynecological malignancies, and it has become a crucial public health problem. In the present study, the expression profiles of cervical cancer and normal cervical tissues were downloaded from the Gene Expression Omnibus and...
Circulating miR-451a levels as a potential biomarker to predict the prognosis of patients with multiple myeloma. Oncol Lett. 2020 Nov;20(5):263 Authors: Zhong L, Jin X, Xu Z, Zeng M, Chen D, He Y, Zhang J, Jiang T, Chen J Abstract The natural course of multiple myeloma (MM) varies greatly between patients. The Revised MM International Staging System (R-ISS) identifies high-risk patients, but it is unsuitable for assessing minimal residual disease...
miR-138-5p suppresses glioblastoma cell viability and leads to cell cycle arrest by targeting cyclin D3. Oncol Lett. 2020 Nov;20(5):264 Authors: Wu H, Wang C, Liu Y, Yang C, Liang X, Zhang X, Li X Abstract Although malignant glioblastoma (GBM) treatment has significantly improved in the past few decades, the prognosis of GBM remains unsatisfactory. MicroRNA (miR)-138-5p has been reported as a tumor suppressor in several types of human cancer;...
Diabetes and PKM2 affect prognosis in patients with intrahepatic cholangiocarcinoma. Oncol Lett. 2020 Nov;20(5):265 Authors: Fu K, Yang X, Wu H, Gong J, Li X Abstract Diabetes mellitus (DM) is a common disease, but its effect on the prognosis of patients with intrahepatic cholangiocarcinoma (ICC) has not been reported. The aim of the present study was to explore the prognostic significance of diabetes in patients with ICC treated with hepatectomy...
Esophageal squamous cell cancer coincides with myelodysplastic syndrome/acute myelogenous leukemia: A case report and review of the literature. Oncol Lett. 2020 Nov;20(5):266 Authors: Liu L, Liu X, Sun Y, Zeng Y, Tang X, Li X, Liu J, Xiao R Abstract Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors, and has high incidence and mortality rates, worldwide. Myelodysplastic syndrome (MDS), a disorder of hematopoietic...
Radiographical efficacy of systemic treatment for bone metastasis from renal cell carcinoma. Oncol Lett. 2020 Nov;20(5):267 Authors: Negishi T, Furubayashi N, Takamatsu D, Ieiri K, Nishiyama N, Kitamura H, Nakamura M Abstract Enlarged bone metastasis from renal cell carcinoma (RCC) can cause skeletal-related events, and thus treatment to inhibit the growth of bone metastases is often required. Although radiotherapy for RCC bone metastases can...
Role of Wnt5a in suppressing invasiveness of hepatocellular carcinoma via epithelial-mesenchymal transition. Oncol Lett. 2020 Nov;20(5):268 Authors: Wakizaka K, Kamiyama T, Wakayama K, Orimo T, Shimada S, Nagatsu A, Kamachi H, Yokoo H, Fukai M, Kobayashi N, Mitsuhashi T, Taketomi A Abstract Inappropriate activation of the canonical Wnt signaling pathway is associated with progression of hepatocellular carcinoma (HCC). However, the association...
Novel technical modifications of hand-assisted laparoscopic dissection of a large obturator mass: A case report and literature review. Oncol Lett. 2020 Nov;20(5):269 Authors: Zhang J, Zhong P, Tong H, Jiang J, Tong D Abstract Laparoscopic lateral pelvic tumor dissection (LLPTD) for transobturator tumors may be technically challenging due to the requirement for sufficient operative space. The present study discusses a technique modification...
Agaricus blazei extract (FA-2-b-β) induces apoptosis in chronic myeloid leukemia cells. Oncol Lett. 2020 Nov;20(5):270 Authors: Sun Y, Cheng M, Dong L, Yang K, Ma Z, Yu S, Yan P, Bai K, Zhu X, Zhang Q Abstract Agaricus blazei Murill (AbM) is a mushroom belonging to the Basidiomycetes family, which is believed to have antitumor and antioxidative activities. Proteoglycans and ergosterol are considered the key compounds of AbM for antitumor properties...
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