Is antibiotic prophylaxis expendable in parotid gland surgery? A retrospective analysis of surgical site infection rates

xlomafota13 shared this article with you from Inoreader Is antibiotic prophylaxis expendable in parotid gland surgery? A retrospective analysis of surgical site infection rates Via Clinical Otolaryngology Abstract Objectives To evaluate the rate of surgical site infection (SSI) and associated risk factors after parotid gland surgery including the impact of antibiotic prophylaxis. Design Retrospective single‐center clinical study. Setting Tertiary referral center for head and neck surgery Participants 754 patients who underwent parotid gland surgery at the University Hospital Heidelberg, Germany between 2007 and 2014 were enrolled in this study. Data on patient age, American Society of Anesthesiologists (ASA) classification system, smoking status, diabetes mellitus, operation time, and antibiotic prophylaxis were collected. Additionally, the National Healthcare Safety Network (NHSN) risk index was calculated. Association of these factors with SSI was evaluated in univariate analyses and a multivariate logistic regression model. Main outcome measures Rate of SSI. Results 24 patients (3.2%) had an SSI according to the NHSN definition. In univariate analyses, only smokers (p = 0.048) and male patients (p = 0.01) had a significantly higher rate of SSI. Since the majority of smokers were men (62.3%), the effect of male gender, smoking, together with the NHSN risk index were further investigated as predictors of SSI within a logistic regression model. All three predictors showed a significant effect on SSI. Conclusions Parotid gland surgery has a low rate of SSI. In our cohort, male gender, smoking, and high NHSN risk index scores were significantly associated with SSI, whereas antibiotic prophylaxis had no protective effect. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.