Differentiated Thyroid Carcinoma: Distant Metastasis as an Unusual Sole Initial Manifestation

xlomafota13 shared this article with you from Inoreader Differentiated Thyroid Carcinoma: Distant Metastasis as an Unusual Sole Initial Manifestation Via radioactive iodine Turk Arch Otorhinolaryngol. 2021 Sep;59(3):188-192. doi: 10.4274/tao.2021.2021-2-5. Epub 2021 Oct 15. ABSTRACT OBJECTIVE: The objective of this study was to identify the characteristic features of patients with distant metastasis as the only manifestation of well-differentiated thyroid cancers and to analyze the treatment outcomes. METHODS: A retrospective review of all patients with well-differentiated thyroid cancers and distant metastasis as the sole initial presentation w as carried out. Data regarding age, gender, tumor histology, site, symptoms, and treatment outcomes were collected. RESULTS: There were 10 patients who presented with distant metastasis as the only presentation. The mean age was 56.1 years. Eight (80%) patients had osseous metastasis, one (10%) had pulmonary and one (10%) had both. Follicular thyroid carcinoma was more common and seen in six (60%) patients. Seven (77.8%) out of nine patients had demised within five years of initial presentation. CONCLUSION: Distant metastases without a neck lump as the initial presentation of well-differentiated thyroid cancers are extremely rare. No specific guidelines are available to manage such patients due to lack of relevant data in the literature. PMID:34713003 | PMC:PMC8527540 | DOI:10.4274/tao.2021.2021-2-5 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.