PRENATAL VITAMIN COMPOUNDS AVAILABLE IN BRAZIL ARE NOT SUITABLE FOR ADEQUATE IODINE SUPPLEMENTATION OF PREGNANT WOMEN.

PRENATAL VITAMIN COMPOUNDS AVAILABLE IN BRAZIL ARE NOT SUITABLE FOR ADEQUATE IODINE SUPPLEMENTATION OF PREGNANT WOMEN.

Thyroid. 2015 Dec 23;

Authors: Villagelin D, Romaldini JH, Comarella AP, Azevedo GG, Zolio SC, Tiago DB, Ward LS

Abstract
Maternal intake iodine deficiency, results in altered maternal and fetal hormone synthesis, which is proportional to the degree and duration of the iodine deprivation. A recent meta-analysis demonstrated difference in the prevalence of iodine deficiency disorders in individuals of different ages living in different regions of Brazil. Worryingly, the Brazilian National Health Surveillance (ANVISA) recently reduced the amount of iodine added to salt. Here we aimed to: 1) identify the availability of dietary supplements for pregnant women in Brazil; 2) verify the amount of iodine present in these supplements; and 3) correlate these levels with the new global recommendations of the American Thyroid Association (1). We obtained nutritional information from available dietary supplements used by pregnant women and analyzed these data based on information on their package insert using the federal agency (ANVISA) system of drug control and regulation; the Anvisa's Eletronic Label. We identified 25 dietary supplements for pregnant women currently in use in Brazil. Based on the minimal daily supplementation of 150 µg of iodine recommended by the ATA, the ETA and the WHO, 48% of these supplements contained no iodine (12 out of the 25 products), 16% (4) contained 1 to 149 µg of iodine, and only 9 products (36%) had the recommended amount of iodine. In fact, despite a mandatory program of salt iodization in Brazil, available studies have found iodine insufficiency in 30 to 57% of brazilian pregnant women. On the other hand, less than half of dietary supplements commercially available and used by pregnant women in Brazil contain iodine at the amounts recommended by international guidelines. Based on our findings, we propose that urgent measures are needed to protect both pregnant women and their offspring from the severe consequences associated with iodine deficiency.

PMID: 26700644 [PubMed - as supplied by publisher]

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