Optogenetic control of nuclear protein export

Article

Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional activity.

Nature Communications doi: 10.1038/ncomms10624

Authors: Dominik Niopek, Pierre Wehler, Julia Roensch, Roland Eils, Barbara Di Ventura

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