Hand, foot and mouth disease: an overview of clinical features in adult patients

Abstract

Hand, foot and mouth disease (HFMD) mainly affects children aged <5 years and is caused by several serotypes of enteroviruses, more frequently Enterovirus 71 (EV71) and Coxsackie A16 (CA16)¹. The disease presents with vesicles in the mouth, hands, feet and buttocks. Only 1% of infected adults develop clinical manifestations, probably as a result of immunological memory¹_. Nevertheless, in the atypical HFMD caused by Coxsackie virus A6 (CVA6) the involvement of immunocompetent adults has been recently described^2-6.

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