Related Articles |
Value of serial magnetic resonance imaging in the assessment of brain metastases volume control during stereotactic radiosurgery.
World J Radiol. 2016 Dec 28;8(12):916-921
Authors: Sparacia G, Agnello F, Banco A, Bencivinni F, Anastasi A, Giordano G, Taibbi A, Galia M, Bartolotta TV
Abstract
AIM: To evaluate brain metastases volume control capabilities of stereotactic radiosurgery (SRS) through serial magnetic resonance (MR) imaging follow-up.
METHODS: MR examinations of 54 brain metastases in 31 patients before and after SRS were reviewed. Patients were included in this study if they had a pre-treatment MR examination and serial follow-up MR examinations at 6 wk, 9 wk, 12 wk, and 12 mo after SRS. The metastasis volume change was categorized at each follow-up as increased (> 20% of the initial volume), stable (± 20% of the initial volume) or decreased (< 20% of the initial volume).
RESULTS: A local tumor control with a significant (P < 0.05) volume decrease was observed in 25 metastases at 6-wk follow-up. Not significant volume change was observed in 23 metastases and a significant volume increase was observed in 6 metastases. At 9-wk follow-up, 15 out of 25 metastases that decreased in size at 6 wk had a transient tumor volume increase, followed by tumor regression at 12 wk. At 12-wk follow-up there was a significant reduction in volume in 45 metastases, and a significant volume increase in 4 metastases. At 12-mo follow-up, 19 metastases increased significantly in size (up to 41% of the initial volume). Volume tumor reduction was correlated to histopathologic subtype.
CONCLUSION: SRS provided an effective local brain metastases volume control that was demonstrated at follow-up MR imaging.
PMID: 28070243 [PubMed - in process]
http://ift.tt/2iJ2rVH
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου