Frozen Sections in Patients Undergoing Breast Conserving Surgery at a Single Ambulatory Surgical Center: 5 Year Experience

Publication date: Available online 6 February 2017
Source:European Journal of Surgical Oncology (EJSO)
Author(s): Julie M. Jorns, Stephanie Daignault, Michael S. Sabel, Jeffrey L. Myers, Angela J. Wu
ObjectivesTo evaluate outcomes of our breast frozen section (FS) practice in its first 5 years, including our specialized FS of margins (FSM) procedure for breast conserving therapy (BCT) patients.Methods1248 patients undergoing 1303 breast FSM and/or sentinel lymph node (SLN) FS were included. Clinicopathologic features were assessed by chart review.ResultsUse of SLN FS declined, from 43.5% of FS cases before to 19.2% of FS cases after 2012. FSM patients had a decline in overall reexcision to 12.3% in 2013-2014 (p=0.063). There was also decline in reexcision for focally close margins (p<0.0001) but no change in reexcision for extensively close margins. Reexcision was significantly associated with lobular subtype, multifocality and larger (≥T2) size. False negative FSM cases were most often influenced by extensively close or positive final (reexcised) margins sent for permanent section only (96/148; 64.9%).ConclusionsDespite changing surgical practices, FSM remains a valuable service that reduces reexcision in BCT patients.



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